Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AYN42_RS17925 Genome accession   NZ_CP027352
Coordinates   3180334..3180966 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2012C-4606     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3175334..3185966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYN42_RS17895 yheS 3175503..3177416 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AYN42_RS17900 yheT 3177416..3178438 (+) 1023 WP_000057356.1 hydrolase -
  AYN42_RS17905 yheU 3178432..3178650 (+) 219 WP_000907085.1 YheU family protein -
  AYN42_RS17910 prkB 3178704..3179573 (+) 870 WP_001274680.1 phosphoribulokinase -
  AYN42_RS17915 yhfA 3179628..3180032 (-) 405 WP_001148908.1 OsmC family protein -
  AYN42_RS17925 crp 3180334..3180966 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AYN42_RS17930 yhfK 3181017..3183107 (+) 2091 WP_012817819.1 YccS/YhfK family putative transporter -
  AYN42_RS17935 argD 3183174..3184394 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AYN42_RS17940 pabA 3184480..3185043 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AYN42_RS17945 fic 3185075..3185677 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AYN42_RS17950 yhfG 3185667..3185834 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232697 AYN42_RS17925 WP_000242755.1 3180334..3180966(+) (crp) [Escherichia coli strain 2012C-4606]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232697 AYN42_RS17925 WP_000242755.1 3180334..3180966(+) (crp) [Escherichia coli strain 2012C-4606]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467