Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ND05_RS29485 Genome accession   NZ_CP027351
Coordinates   5434054..5434686 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3655     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5429054..5439686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ND05_RS29455 yheS 5429223..5431136 (+) 1914 WP_000634793.1 ABC transporter ATP-binding protein -
  ND05_RS29460 yheT 5431136..5432158 (+) 1023 WP_000057359.1 hydrolase -
  ND05_RS29465 yheU 5432152..5432370 (+) 219 WP_000907085.1 YheU family protein -
  ND05_RS29470 prkB 5432424..5433293 (+) 870 WP_001274680.1 phosphoribulokinase -
  ND05_RS29475 yhfA 5433348..5433752 (-) 405 WP_001148908.1 OsmC family protein -
  ND05_RS29485 crp 5434054..5434686 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  ND05_RS29490 yhfK 5434737..5436827 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  ND05_RS29495 argD 5436894..5438114 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  ND05_RS29500 pabA 5438200..5438763 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  ND05_RS29505 fic 5438795..5439397 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  ND05_RS29510 yhfG 5439387..5439554 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232660 ND05_RS29485 WP_000242755.1 5434054..5434686(+) (crp) [Escherichia coli strain 2014C-3655]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232660 ND05_RS29485 WP_000242755.1 5434054..5434686(+) (crp) [Escherichia coli strain 2014C-3655]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment