Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AZF34_RS19715 Genome accession   NZ_CP027347
Coordinates   3610473..3611105 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4361     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3605473..3616105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZF34_RS19685 yheS 3605642..3607555 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AZF34_RS19690 yheT 3607555..3608577 (+) 1023 WP_000057362.1 hydrolase -
  AZF34_RS19695 yheU 3608571..3608789 (+) 219 WP_000907085.1 YheU family protein -
  AZF34_RS19700 prkB 3608843..3609712 (+) 870 WP_001274680.1 phosphoribulokinase -
  AZF34_RS19705 yhfA 3609767..3610171 (-) 405 WP_001148909.1 OsmC family protein -
  AZF34_RS19715 crp 3610473..3611105 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AZF34_RS19720 yhfK 3611156..3613246 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AZF34_RS19725 argD 3613313..3614533 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AZF34_RS19730 pabA 3614619..3615182 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AZF34_RS19735 fic 3615214..3615816 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AZF34_RS19740 yhfG 3615806..3615973 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232549 AZF34_RS19715 WP_000242755.1 3610473..3611105(+) (crp) [Escherichia coli strain 2013C-4361]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232549 AZF34_RS19715 WP_000242755.1 3610473..3611105(+) (crp) [Escherichia coli strain 2013C-4361]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467