Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6N23_RS05805 Genome accession   NZ_CP027342
Coordinates   1174190..1174822 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-4587     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1169190..1179822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N23_RS05780 yhfG 1169322..1169489 (+) 168 WP_000736860.1 YhfG family protein -
  C6N23_RS05785 fic 1169479..1170081 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6N23_RS05790 pabA 1170113..1170676 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  C6N23_RS05795 argD 1170762..1171982 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6N23_RS05800 yhfK 1172049..1174139 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  C6N23_RS05805 crp 1174190..1174822 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6N23_RS05815 yhfA 1175124..1175528 (+) 405 WP_001148908.1 OsmC family protein -
  C6N23_RS05820 prkB 1175583..1176452 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6N23_RS05825 yheU 1176506..1176724 (-) 219 WP_000907085.1 YheU family protein -
  C6N23_RS05830 yheT 1176718..1177740 (-) 1023 WP_000057405.1 hydrolase -
  C6N23_RS05835 yheS 1177740..1179653 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232449 C6N23_RS05805 WP_000242755.1 1174190..1174822(-) (crp) [Escherichia coli strain 2014C-4587]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232449 C6N23_RS05805 WP_000242755.1 1174190..1174822(-) (crp) [Escherichia coli strain 2014C-4587]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467