Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6N28_RS19545 Genome accession   NZ_CP027338
Coordinates   3510515..3511147 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3051     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3505515..3516147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N28_RS19515 yheS 3505685..3507598 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6N28_RS19520 yheT 3507598..3508619 (+) 1022 Protein_3612 hydrolase -
  C6N28_RS19525 yheU 3508613..3508831 (+) 219 WP_000907085.1 YheU family protein -
  C6N28_RS19530 prkB 3508885..3509754 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6N28_RS19535 yhfA 3509809..3510213 (-) 405 WP_001148908.1 OsmC family protein -
  C6N28_RS19545 crp 3510515..3511147 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6N28_RS19550 yhfK 3511198..3513288 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6N28_RS19555 argD 3513355..3514575 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6N28_RS19560 pabA 3514661..3515224 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6N28_RS19565 fic 3515256..3515857 (-) 602 Protein_3620 putative adenosine monophosphate-protein transferase Fic -
  C6N28_RS19570 yhfG 3515847..3516014 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232304 C6N28_RS19545 WP_000242755.1 3510515..3511147(+) (crp) [Escherichia coli strain 2014C-3051]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232304 C6N28_RS19545 WP_000242755.1 3510515..3511147(+) (crp) [Escherichia coli strain 2014C-3051]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467