Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   MJ63_RS18740 Genome accession   NZ_CP027331
Coordinates   3402082..3402714 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-3277     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3397082..3407714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MJ63_RS18710 yheS 3397251..3399164 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  MJ63_RS18715 yheT 3399164..3400186 (+) 1023 WP_000057356.1 hydrolase -
  MJ63_RS18720 yheU 3400180..3400398 (+) 219 WP_000907085.1 YheU family protein -
  MJ63_RS18725 prkB 3400452..3401321 (+) 870 WP_001274680.1 phosphoribulokinase -
  MJ63_RS18730 yhfA 3401376..3401780 (-) 405 WP_001148908.1 OsmC family protein -
  MJ63_RS18740 crp 3402082..3402714 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  MJ63_RS18745 yhfK 3402765..3404855 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  MJ63_RS18750 argD 3404922..3406142 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  MJ63_RS18755 pabA 3406228..3406791 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  MJ63_RS18760 fic 3406823..3407425 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  MJ63_RS18765 yhfG 3407415..3407582 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232226 MJ63_RS18740 WP_000242755.1 3402082..3402714(+) (crp) [Escherichia coli strain 2013C-3277]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232226 MJ63_RS18740 WP_000242755.1 3402082..3402714(+) (crp) [Escherichia coli strain 2013C-3277]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment