Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C6N27_RS23450 Genome accession   NZ_CP027307
Coordinates   4358824..4359414 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 2015C-3108     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4353824..4364414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N27_RS23405 emrD 4354306..4355490 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  C6N27_RS30510 ysdE 4355572..4355646 (+) 75 WP_211180519.1 protein YsdE -
  C6N27_RS23415 tisB 4355909..4355998 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  C6N27_RS23435 ivbL 4356563..4356661 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  C6N27_RS23440 ilvB 4356767..4358455 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  C6N27_RS23445 ilvN 4358459..4358749 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  C6N27_RS23450 letA 4358824..4359414 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  C6N27_RS23455 uhpB 4359414..4360916 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  C6N27_RS23460 uhpC 4360926..4362245 (+) 1320 WP_001341770.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  C6N27_RS23465 uhpT 4362501..4363892 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=231769 C6N27_RS23450 WP_000633668.1 4358824..4359414(+) (letA) [Escherichia coli strain 2015C-3108]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=231769 C6N27_RS23450 WP_000633668.1 4358824..4359414(+) (letA) [Escherichia coli strain 2015C-3108]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment