Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6H98_RS25300 Genome accession   NZ_CP027221
Coordinates   4709598..4710230 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2015C-3101     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4704598..4715230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6H98_RS25270 yheS 4704767..4706680 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C6H98_RS25275 yheT 4706680..4707702 (+) 1023 WP_000057362.1 hydrolase -
  C6H98_RS25280 yheU 4707696..4707914 (+) 219 WP_000907085.1 YheU family protein -
  C6H98_RS25285 prkB 4707968..4708837 (+) 870 WP_001274680.1 phosphoribulokinase -
  C6H98_RS25290 yhfA 4708892..4709296 (-) 405 WP_001148909.1 OsmC family protein -
  C6H98_RS25300 crp 4709598..4710230 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6H98_RS25305 yhfK 4710281..4712371 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6H98_RS25310 argD 4712438..4713658 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6H98_RS25315 pabA 4713744..4714307 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  C6H98_RS25320 fic 4714339..4714941 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  C6H98_RS25325 yhfG 4714931..4715098 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=231450 C6H98_RS25300 WP_000242755.1 4709598..4710230(+) (crp) [Escherichia coli strain 2015C-3101]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=231450 C6H98_RS25300 WP_000242755.1 4709598..4710230(+) (crp) [Escherichia coli strain 2015C-3101]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467