Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   WS_RS07580 Genome accession   NC_005090
Coordinates   1519035..1520843 (+) Length   602 a.a.
NCBI ID   WP_011139426.1    Uniprot ID   -
Organism   Wolinella succinogenes DSM 1740     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1514035..1525843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WS_RS07555 (WS1601) tpx 1514357..1514857 (+) 501 WP_011139421.1 thiol peroxidase -
  WS_RS07560 (WS1602) - 1514840..1515484 (-) 645 WP_011139422.1 uroporphyrinogen-III synthase -
  WS_RS07565 (WS1603) guaA 1515484..1517049 (-) 1566 WP_011139423.1 glutamine-hydrolyzing GMP synthase -
  WS_RS07570 (WS1604) nadB 1517072..1518511 (-) 1440 WP_011139424.1 L-aspartate oxidase -
  WS_RS11245 - 1518511..1518639 (-) 129 WP_269470910.1 hypothetical protein -
  WS_RS07575 (WS1606) - 1518631..1519056 (+) 426 WP_011139425.1 hypothetical protein -
  WS_RS07580 (WS1607) uvrC 1519035..1520843 (+) 1809 WP_011139426.1 excinuclease ABC subunit UvrC Machinery gene
  WS_RS10705 (WS1608) - 1520996..1521934 (-) 939 WP_011139427.1 helix-turn-helix transcriptional regulator -
  WS_RS07590 (WS1610) - 1522050..1524044 (+) 1995 WP_011139428.1 TonB-dependent receptor -
  WS_RS07595 (WS1611) - 1524150..1524623 (+) 474 WP_041571864.1 pyridoxamine 5'-phosphate oxidase family protein -
  WS_RS07600 (WS1612) - 1524601..1525383 (-) 783 WP_011139430.1 AraC family transcriptional regulator -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69422.53 Da        Isoelectric Point: 8.7819

>NTDB_id=23084 WS_RS07580 WP_011139426.1 1519035..1520843(+) (uvrC) [Wolinella succinogenes DSM 1740]
MQSETLLETLQNLPDQSGVYHYFDSRSKLLYVGKAKSLKKRVKSYFQFTPTLAPSPKLSPRIHKMISEAAFIRYIVVENE
HDALILENSLIKQLKPKYNILLRDDKTYPYIYFDENESFPRLEITRKILPHKGVRYFGPYTTGARELLESLYELLPLVQK
KGCLKAQKACLFYQIHRCLAPCESKISKERYGEIFKEALGLLQNHSKLISRLKERMEKLAENLRFEEAGELRDRIEKIKR
IEAFSGIDLARLEDLDILAIATSGKHSMLTRLFMREGKVVSSTSTPLKAQEGLDEEEAYRRAILHYYDSFMPLPPKQILL
PLELESKRELEAHLEGLFGRKIPLHHPKQGSKKALIDLALKNAEELLRLEGEKEEIPLLESLQELLGLESLPRRIEAFDT
SHLRGEACVGAMVVYEEGFCKESYRRYALEGRDEYSQMREMLGRRAEAFDRESPPDLWLLDGGLGQIRLAQEIIESLGAN
VEIIAIAKEKIDAKAHRAKGAAKDILRTPTEEIRLLPSDKRLQLLQKIRDEVHRFAITYHRQQKLKKDRQIDLLEIKGIK
KGKLKRLLDFFGSFEAIREASFEELCKVVSEGEARAILEASF

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=23084 WS_RS07580 WP_011139426.1 1519035..1520843(+) (uvrC) [Wolinella succinogenes DSM 1740]
TTGCAATCAGAAACCCTCCTAGAGACCCTTCAAAATCTCCCCGATCAAAGTGGAGTCTATCACTACTTCGATTCTCGCTC
CAAGCTCCTTTATGTGGGTAAAGCCAAGAGCCTCAAAAAGCGCGTGAAGAGCTATTTTCAATTCACGCCGACTCTTGCGC
CCTCACCCAAGCTCTCCCCTCGAATCCACAAAATGATCAGCGAAGCCGCCTTCATCCGCTACATCGTAGTGGAGAACGAA
CACGATGCACTCATCCTTGAAAACTCCCTCATCAAGCAGCTCAAACCCAAATACAACATCCTCCTGCGCGATGACAAAAC
CTACCCCTATATCTATTTTGACGAAAATGAATCCTTCCCTCGCCTAGAGATCACGCGCAAGATTCTCCCCCACAAAGGCG
TGCGCTACTTTGGTCCCTACACCACAGGAGCTAGAGAGCTACTAGAGAGCCTCTATGAGTTGCTCCCTTTGGTGCAAAAA
AAAGGGTGTCTTAAAGCCCAAAAGGCGTGCCTTTTCTATCAGATCCATCGCTGTCTCGCTCCTTGTGAATCCAAAATCTC
CAAAGAGCGCTATGGGGAGATTTTCAAAGAGGCTCTAGGGCTTCTCCAAAACCACTCCAAGCTCATCTCCCGCCTCAAAG
AGAGGATGGAAAAACTGGCAGAGAATCTTCGTTTTGAGGAGGCAGGAGAGCTGAGGGATCGAATCGAAAAGATCAAAAGA
ATCGAAGCCTTCTCTGGAATTGATCTCGCTAGATTAGAGGATCTCGATATTCTCGCCATTGCCACTAGCGGCAAGCACTC
CATGCTTACAAGACTCTTCATGCGCGAAGGCAAGGTGGTCTCTAGCACCAGCACTCCGCTCAAAGCCCAAGAGGGGCTGG
ATGAAGAAGAGGCCTATAGGCGTGCGATTCTTCACTATTACGACTCTTTCATGCCCCTCCCCCCCAAGCAGATTCTTCTT
CCTTTGGAGCTTGAATCCAAAAGAGAGCTTGAGGCTCATCTTGAGGGGCTTTTTGGACGAAAAATCCCCCTTCATCACCC
CAAGCAAGGGAGTAAAAAGGCTCTCATCGACCTTGCTTTGAAAAACGCCGAAGAGCTTTTGAGATTGGAGGGGGAAAAAG
AGGAGATTCCCCTTTTAGAATCGCTTCAAGAACTTTTGGGGCTCGAATCGCTCCCAAGAAGAATCGAAGCCTTTGACACC
TCCCACCTAAGAGGCGAGGCGTGCGTGGGCGCGATGGTGGTCTATGAGGAGGGGTTTTGCAAAGAGAGCTATCGCCGCTA
CGCCCTAGAAGGCAGGGATGAGTATTCACAAATGAGAGAGATGCTGGGGCGCCGCGCTGAAGCATTTGATCGAGAATCGC
CTCCTGATTTGTGGCTTCTTGATGGCGGATTGGGTCAGATTCGACTCGCGCAAGAGATCATTGAGAGCCTTGGAGCCAAT
GTCGAAATCATCGCCATTGCCAAAGAGAAGATTGACGCCAAAGCCCATCGCGCCAAAGGAGCTGCCAAAGATATTCTACG
CACCCCCACCGAGGAGATTCGCCTCCTTCCCAGCGACAAACGCCTCCAGCTGCTACAAAAAATCCGAGATGAGGTGCATC
GATTCGCCATCACCTACCATCGCCAACAAAAACTCAAAAAAGATCGCCAAATCGATCTCCTGGAGATTAAGGGAATCAAA
AAAGGCAAACTCAAGCGGCTTTTGGACTTTTTTGGAAGTTTTGAGGCCATCAGAGAAGCGAGCTTTGAAGAGCTTTGCAA
AGTGGTGAGTGAGGGCGAGGCGAGAGCTATTTTGGAGGCTTCATTTTAG

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)

UvrB/uvrC motif (UVR)

(207-240)

GIY-YIG catalytic domain (GIY-YIG)

(17-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

54.811

96.678

0.53

Multiple sequence alignment