Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   C5099_RS24365 Genome accession   NZ_CP027103
Coordinates   4683571..4684161 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM14723     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4678571..4689161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C5099_RS24350 (C5099_24340) uhpT 4679211..4680602 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  C5099_RS24355 (C5099_24345) uhpC 4680740..4682059 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  C5099_RS24360 (C5099_24350) uhpB 4682069..4683571 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  C5099_RS24365 (C5099_24355) letA 4683571..4684161 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  C5099_RS24370 (C5099_24360) ilvN 4684234..4684524 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  C5099_RS24375 (C5099_24365) ilvB 4684528..4686216 (-) 1689 WP_001357895.1 acetolactate synthase large subunit -
  C5099_RS24380 (C5099_24370) ivbL 4686322..4686420 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  C5099_RS25180 ysdE 4686665..4686739 (-) 75 WP_211180519.1 protein YsdE -
  C5099_RS24390 (C5099_24380) emrD 4686821..4688005 (+) 1185 WP_001304999.1 multidrug efflux MFS transporter EmrD -
  C5099_RS24395 (C5099_24385) yidF 4688013..4688510 (-) 498 WP_000148045.1 radical SAM protein -
  C5099_RS24400 (C5099_24390) yidG 4688507..4688869 (-) 363 WP_001113432.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=230079 C5099_RS24365 WP_000633668.1 4683571..4684161(-) (letA) [Escherichia coli strain RM14723]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=230079 C5099_RS24365 WP_000633668.1 4683571..4684161(-) (letA) [Escherichia coli strain RM14723]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment