Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C4962_RS02055 Genome accession   NZ_CP026929
Coordinates   446301..446933 (-) Length   210 a.a.
NCBI ID   WP_000242761.1    Uniprot ID   -
Organism   Escherichia coli strain CFS3246     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 441301..451933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4962_RS02030 (C4962_02185) yhfG 441433..441600 (+) 168 WP_000736862.1 YhfG family protein -
  C4962_RS02035 (C4962_02190) fic 441590..442192 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C4962_RS02040 (C4962_02195) pabA 442224..442787 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C4962_RS02045 (C4962_02200) argD 442873..444093 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C4962_RS02050 (C4962_02205) yhfK 444160..446250 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C4962_RS02055 (C4962_02210) crp 446301..446933 (-) 633 WP_000242761.1 cAMP-activated global transcriptional regulator CRP Regulator
  C4962_RS02060 (C4962_02220) yhfA 447235..447639 (+) 405 WP_001148908.1 OsmC family protein -
  C4962_RS02065 (C4962_02225) prkB 447694..448563 (-) 870 WP_001274680.1 phosphoribulokinase -
  C4962_RS02070 (C4962_02230) yheU 448617..448835 (-) 219 WP_000907085.1 YheU family protein -
  C4962_RS02075 (C4962_02235) yheT 448829..449851 (-) 1023 WP_000057356.1 hydrolase -
  C4962_RS02080 (C4962_02240) yheS 449851..451764 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23644.41 Da        Isoelectric Point: 8.2710

>NTDB_id=228808 C4962_RS02055 WP_000242761.1 446301..446933(-) (crp) [Escherichia coli strain CFS3246]
MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=228808 C4962_RS02055 WP_000242761.1 446301..446933(-) (crp) [Escherichia coli strain CFS3246]
ATGGTGCTTGGCAAAACGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

78.049

97.619

0.762
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467