Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   AM456_RS04090 Genome accession   NZ_CP026755
Coordinates   645304..647325 (+) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain AR_0077     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 640304..652325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM456_RS04070 (AM456_04070) bioB 641122..642162 (+) 1041 WP_000951213.1 biotin synthase BioB -
  AM456_RS04075 (AM456_04075) bioF 642159..643316 (+) 1158 WP_094030349.1 8-amino-7-oxononanoate synthase -
  AM456_RS04080 (AM456_04080) bioC 643300..644055 (+) 756 WP_094030350.1 malonyl-ACP O-methyltransferase BioC -
  AM456_RS04085 (AM456_04085) bioD 644048..644725 (+) 678 WP_000030920.1 dethiobiotin synthase -
  AM456_RS04090 (AM456_04090) uvrB 645304..647325 (+) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  AM456_RS04095 (AM456_04095) yvcK 647363..648271 (-) 909 WP_032170980.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  AM456_RS04100 (AM456_04100) moaA 648668..649657 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  AM456_RS04105 (AM456_04105) moaB 649679..650191 (+) 513 WP_094030351.1 molybdenum cofactor biosynthesis protein B -
  AM456_RS04110 (AM456_04110) moaC 650194..650679 (+) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  AM456_RS04115 (AM456_04115) moaD 650672..650917 (+) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  AM456_RS04120 (AM456_04120) moaE 650919..651371 (+) 453 WP_000852273.1 molybdopterin synthase catalytic subunit MoaE -
  AM456_RS04125 (AM456_04125) ybhL 651508..652212 (+) 705 WP_001361291.1 Bax inhibitor-1/YccA family protein -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=228529 AM456_RS04090 WP_000042533.1 645304..647325(+) (uvrB) [Escherichia coli strain AR_0077]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=228529 AM456_RS04090 WP_000042533.1 645304..647325(+) (uvrB) [Escherichia coli strain AR_0077]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTCGGTGTAACTGGCTCCGGGAAAACCTTCACCATCGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTGGCGCCCAACAAAACGCTGGCGGCCCAACTGTACGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATTGAGCAGATGCGTTTGTCCGCTACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGCATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGCGGTACTTTCCGCGTTCGTGGTGAGGTGATAGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTAACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGTGAGCGCATCGTACAGGCGATGGAGGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTCGTCGACGAATCTCACGTCACCATTCCACAAAT
TGGTGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTATGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTTGACCCGATTATTGAAGTGCGTCC
GGTAGCGACACAGGTGGATGATCTTCTATCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCAGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557