Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C4R22_RS13460 Genome accession   NZ_CP026723
Coordinates   2569316..2569948 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 266917_2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2564316..2574948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4R22_RS13430 yheS 2564479..2566398 (+) 1920 WP_001551739.1 ABC transporter ATP-binding protein -
  C4R22_RS13435 yheT 2566398..2567420 (+) 1023 WP_001551740.1 hydrolase -
  C4R22_RS13440 yheU 2567414..2567632 (+) 219 WP_000907085.1 YheU family protein -
  C4R22_RS13445 prkB 2567686..2568555 (+) 870 WP_001274680.1 phosphoribulokinase -
  C4R22_RS13450 yhfA 2568610..2569014 (-) 405 WP_001148908.1 OsmC family protein -
  C4R22_RS13460 crp 2569316..2569948 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C4R22_RS13465 yhfK 2569999..2572089 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C4R22_RS13470 argD 2572152..2573375 (-) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C4R22_RS13475 pabA 2573461..2574024 (-) 564 WP_001551743.1 aminodeoxychorismate synthase component 2 -
  C4R22_RS13480 fic 2574056..2574658 (-) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  C4R22_RS13485 yhfG 2574648..2574815 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=228318 C4R22_RS13460 WP_000242755.1 2569316..2569948(+) (crp) [Escherichia coli strain 266917_2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=228318 C4R22_RS13460 WP_000242755.1 2569316..2569948(+) (crp) [Escherichia coli strain 266917_2]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467