Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2Q99_RS18245 Genome accession   NZ_CP026361
Coordinates   3486129..3486761 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 1A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3481129..3491761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2Q99_RS18215 yheS 3481298..3483211 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2Q99_RS18220 yheT 3483211..3484233 (+) 1023 WP_000057356.1 hydrolase -
  C2Q99_RS18225 yheU 3484227..3484445 (+) 219 WP_000907085.1 YheU family protein -
  C2Q99_RS18230 prkB 3484499..3485368 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2Q99_RS18235 yhfA 3485423..3485827 (-) 405 WP_001148908.1 OsmC family protein -
  C2Q99_RS18245 crp 3486129..3486761 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2Q99_RS18250 yhfK 3486812..3488902 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2Q99_RS18255 argD 3488969..3490189 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2Q99_RS18260 pabA 3490275..3490838 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2Q99_RS18265 fic 3490870..3491472 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2Q99_RS18270 yhfG 3491462..3491629 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=227039 C2Q99_RS18245 WP_000242755.1 3486129..3486761(+) (crp) [Escherichia coli strain 1A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=227039 C2Q99_RS18245 WP_000242755.1 3486129..3486761(+) (crp) [Escherichia coli strain 1A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467