Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2R12_RS18245 Genome accession   NZ_CP026351
Coordinates   3486120..3486752 (+) Length   210 a.a.
NCBI ID   WP_104959171.1    Uniprot ID   -
Organism   Escherichia coli strain 5A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3481120..3491752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2R12_RS18215 yheS 3481289..3483202 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2R12_RS18220 yheT 3483202..3484224 (+) 1023 WP_000057356.1 hydrolase -
  C2R12_RS18225 yheU 3484218..3484436 (+) 219 WP_000907085.1 YheU family protein -
  C2R12_RS18230 prkB 3484490..3485359 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2R12_RS18235 yhfA 3485414..3485818 (-) 405 WP_001148908.1 OsmC family protein -
  C2R12_RS18245 crp 3486120..3486752 (+) 633 WP_104959171.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2R12_RS18250 yhfK 3486803..3488893 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2R12_RS18255 argD 3488960..3490180 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2R12_RS18260 pabA 3490266..3490829 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2R12_RS18265 fic 3490861..3491463 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2R12_RS18270 yhfG 3491453..3491620 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23606.41 Da        Isoelectric Point: 8.2710

>NTDB_id=226219 C2R12_RS18245 WP_104959171.1 3486120..3486752(+) (crp) [Escherichia coli strain 5A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLALLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=226219 C2R12_RS18245 WP_104959171.1 3486120..3486752(+) (crp) [Escherichia coli strain 5A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGCTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

77.451

97.143

0.752
  crp Acinetobacter baumannii D1279779

46.86

98.571

0.462

Multiple sequence alignment