Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   SPYM18_RS09315 Genome accession   NC_003485
Coordinates   1825989..1826585 (-) Length   198 a.a.
NCBI ID   WP_011018315.1    Uniprot ID   Q8NZ27
Organism   Streptococcus pyogenes MGAS8232     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1820989..1831585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS09280 (spyM18_2170) - 1821050..1821355 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  SPYM18_RS09285 (spyM18_2171) ruvX 1821367..1821786 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  SPYM18_RS09290 (spyM18_2172) - 1821783..1822052 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  SPYM18_RS09295 (spyM18_2173) spx 1822165..1822563 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  SPYM18_RS09300 (spyM18_2174) recA 1822854..1823990 (-) 1137 WP_002982186.1 recombinase RecA -
  SPYM18_RS09305 (spyM18_2175) cinA 1824079..1825350 (-) 1272 WP_011018313.1 competence/damage-inducible protein A Machinery gene
  SPYM18_RS09310 (spyM18_2176) - 1825419..1825979 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  SPYM18_RS09315 (spyM18_2177) ruvA 1825989..1826585 (-) 597 WP_011018315.1 Holliday junction branch migration protein RuvA Machinery gene
  SPYM18_RS09320 (spyM18_2178) - 1826587..1827807 (-) 1221 WP_011018316.1 MDR family MFS transporter -
  SPYM18_RS09325 (spyM18_2179) hexB 1827818..1829800 (-) 1983 WP_011018317.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21828.22 Da        Isoelectric Point: 7.3105

>NTDB_id=22619 SPYM18_RS09315 WP_011018315.1 1825989..1826585(-) (ruvA) [Streptococcus pyogenes MGAS8232]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTKDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=22619 SPYM18_RS09315 WP_011018315.1 1825989..1826585(-) (ruvA) [Streptococcus pyogenes MGAS8232]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGGTTTCACACGAAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NZ27

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae R6

65.99

99.495

0.657
  ruvA Streptococcus pneumoniae D39

65.99

99.495

0.657
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment