Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2R19_RS18245 Genome accession   NZ_CP026344
Coordinates   3486120..3486752 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 8FA     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3481120..3491752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2R19_RS18215 yheS 3481289..3483202 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2R19_RS18220 yheT 3483202..3484224 (+) 1023 WP_000057356.1 hydrolase -
  C2R19_RS18225 yheU 3484218..3484436 (+) 219 WP_000907085.1 YheU family protein -
  C2R19_RS18230 prkB 3484490..3485359 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2R19_RS18235 yhfA 3485414..3485818 (-) 405 WP_001148908.1 OsmC family protein -
  C2R19_RS18245 crp 3486120..3486752 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2R19_RS18250 yhfK 3486803..3488893 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2R19_RS18255 argD 3488960..3490180 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2R19_RS18260 pabA 3490266..3490829 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2R19_RS18265 fic 3490861..3491463 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2R19_RS18270 yhfG 3491453..3491620 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=225645 C2R19_RS18245 WP_000242755.1 3486120..3486752(+) (crp) [Escherichia coli strain 8FA]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=225645 C2R19_RS18245 WP_000242755.1 3486120..3486752(+) (crp) [Escherichia coli strain 8FA]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment