Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2U48_RS16685 Genome accession   NZ_CP026202
Coordinates   3132435..3133067 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain ECONIH5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3127435..3138067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2U48_RS16660 (C2U48_16645) yhfG 3127568..3127735 (+) 168 WP_000736860.1 YhfG family protein -
  C2U48_RS16665 (C2U48_16650) fic 3127725..3128327 (+) 603 WP_001549769.1 putative adenosine monophosphate-protein transferase Fic -
  C2U48_RS16670 (C2U48_16655) pabA 3128359..3128922 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2U48_RS16675 (C2U48_16660) argD 3129008..3130228 (+) 1221 WP_000963824.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2U48_RS16680 (C2U48_16665) yhfK 3130294..3132384 (-) 2091 WP_001325239.1 YccS/YhfK family putative transporter -
  C2U48_RS16685 (C2U48_16670) crp 3132435..3133067 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2U48_RS16695 (C2U48_16680) yhfA 3133369..3133773 (+) 405 WP_001148908.1 OsmC family protein -
  C2U48_RS16700 (C2U48_16685) prkB 3133828..3134697 (-) 870 WP_001274680.1 phosphoribulokinase -
  C2U48_RS16705 (C2U48_16690) yheU 3134751..3134969 (-) 219 WP_000907085.1 YheU family protein -
  C2U48_RS16710 (C2U48_16695) yheT 3134963..3135985 (-) 1023 WP_000057356.1 hydrolase -
  C2U48_RS16715 (C2U48_16700) yheS 3135985..3137898 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=225033 C2U48_RS16685 WP_000242755.1 3132435..3133067(-) (crp) [Escherichia coli strain ECONIH5]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=225033 C2U48_RS16685 WP_000242755.1 3132435..3133067(-) (crp) [Escherichia coli strain ECONIH5]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACCCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467