Detailed information NTG0224952

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: B6N58_RS01610
• Genome accession: NZ_CP020614
• Coordinates: 345987..347069 (-)
• Length: 360 a.a.
• NCBI ID: WP_045098246.1
• Uniprot ID: A0A098GB34
• Organism: Legionella micdadei strain NZ2015
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 340987..352069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B6N58_RS01590 (B6N58_01590)	-	341955..342392 (+)	438	WP_045098242.1	hypothetical protein	-
B6N58_RS01595 (B6N58_01595)	-	342505..343128 (-)	624	WP_083011742.1	HAD hydrolase-like protein	-
B6N58_RS01600 (B6N58_01600)	topA	343257..345536 (-)	2280	WP_045098244.1	type I DNA topoisomerase	-
B6N58_RS01605 (B6N58_01605)	-	345566..345997 (-)	432	WP_045098245.1	DUF494 family protein	-
B6N58_RS01610 (B6N58_01610)	dprA	345987..347069 (-)	1083	WP_045098246.1	DNA-processing protein DprA	Machinery gene
B6N58_RS01615 (B6N58_01615)	def	347164..347676 (+)	513	WP_045098247.1	peptide deformylase	-
B6N58_RS01620 (B6N58_01620)	fmt	347673..348617 (+)	945	WP_045098248.1	methionyl-tRNA formyltransferase	-
B6N58_RS01625 (B6N58_01625)	rsmB	348614..349894 (+)	1281	WP_045098249.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
B6N58_RS01630 (B6N58_01630)	-	349938..350684 (+)	747	WP_045098250.1	CPBP family glutamic-type intramembrane protease	-
B6N58_RS01635 (B6N58_01635)	-	350773..351282 (+)	510	WP_045098251.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 39640.66 Da
• Isoelectric Point: 6.7529

>NTDB_id=224952 B6N58_RS01610 WP_045098246.1 345987..347069(-) (dprA) [Legionella micdadei strain NZ2015]
MDNKYYLLALNRIQQIGPRTILKLLTYWPKLEEMFRLTSEQLQTAGLTPQLAESICQFDFSEVDVDLRWEEETNHHLLTW
DDPNYPLLLKEIHDPPPVLYLQGNASSLHQASIAIVGSRKPSITGAETAKRFSFELALSQLTVISGLALGIDAQAHQGCI
EANGLTIAILGTGIDCVYPRQHGQLAQKICEKGLLVSEFPLKVGPKAGHFPRRNRIISGLALATLVVEATIRSGSLITAR
LALEQNRDVLAIPGSIYNPQARGCHHLLQQGAKLVTSSQEVIEELGLDNLVIKQSNTTQSLARDNKNLVKCIGFEITTVD
QIVRRSSLSVEEVACGLATLEIQGIIKAVPGGYMRCSYER

Nucleotide

• Length: 1083 bp

>NTDB_id=224952 B6N58_RS01610 WP_045098246.1 345987..347069(-) (dprA) [Legionella micdadei strain NZ2015]
ATGGATAACAAATATTATTTGCTCGCCCTTAACAGAATCCAACAAATCGGCCCAAGGACAATTCTAAAGCTGCTAACCTA
TTGGCCTAAGCTCGAAGAAATGTTTCGATTAACCTCCGAGCAATTGCAAACAGCCGGACTCACACCACAACTTGCCGAGT
CAATTTGCCAGTTTGATTTTAGCGAAGTCGATGTAGATTTACGTTGGGAAGAAGAAACCAATCACCATTTATTGACTTGG
GATGATCCTAATTACCCGTTGTTACTTAAAGAAATTCATGATCCGCCACCTGTTTTGTATTTACAAGGCAACGCTTCAAG
CCTCCATCAAGCGTCAATTGCGATTGTCGGTAGTCGTAAACCATCAATAACTGGTGCAGAAACCGCTAAGCGTTTTTCTT
TTGAATTAGCTTTAAGCCAACTAACGGTTATCAGCGGCCTCGCTTTAGGCATCGATGCCCAAGCTCATCAAGGATGCATA
GAGGCTAATGGTCTAACCATCGCCATTTTAGGAACAGGAATCGACTGCGTTTACCCACGACAACATGGCCAACTCGCACA
AAAAATTTGCGAGAAAGGTTTATTGGTGAGTGAATTTCCCTTAAAGGTAGGTCCCAAAGCTGGACATTTCCCTCGTAGAA
ATCGTATAATAAGCGGTTTGGCATTAGCTACGTTAGTGGTTGAAGCAACCATTCGGAGCGGCTCATTGATTACAGCGCGC
CTCGCTTTGGAACAAAATCGCGACGTATTAGCCATACCAGGCTCTATTTACAACCCGCAAGCGCGCGGCTGTCATCATCT
ACTGCAACAAGGAGCAAAATTAGTTACATCAAGTCAAGAAGTAATTGAAGAGCTAGGACTGGATAACCTAGTTATAAAGC
AAAGTAATACGACGCAATCCCTTGCCAGAGATAACAAAAACCTAGTAAAGTGCATTGGCTTTGAAATTACGACTGTTGAT
CAAATTGTTAGGCGAAGCAGTTTAAGTGTTGAAGAGGTAGCTTGTGGTCTAGCCACACTGGAAATACAGGGTATCATTAA
AGCCGTACCCGGGGGTTATATGAGGTGTTCATATGAAAGATAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-276)

• DprA winged helix domain (DprA_WH) (297-352)

3D structure

• AlphaFold DB: A0A098GB34

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	60.111	100	0.603
dprA	Vibrio campbellii strain DS40M4	46.809	91.389	0.428
dprA	Vibrio cholerae strain A1552	42.5	100	0.425
dprA	Glaesserella parasuis strain SC1401	40.489	100	0.414