Detailed information NTG0224606

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: B7L42_RS12085
• Genome accession: NZ_CP020590
• Coordinates: 2408120..2408785 (+)
• Length: 221 a.a.
• NCBI ID: WP_000203219.1
• Uniprot ID: A0A219CAS9
• Organism: Acinetobacter baumannii strain 15A34
• Function: regulate competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2406029..2409932	2408120..2408785	within	0

Gene organization within MGE regions

Location: 2406029..2409932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B7L42_RS12080 (B7L42_12080)	-	2407259..2407681 (-)	423	WP_001195082.1	OsmC family protein	-
B7L42_RS19350	-	2407760..2407879 (-)	120	Protein_2275	hypothetical protein	-
B7L42_RS12085 (B7L42_12085)	crp	2408120..2408785 (+)	666	WP_000203219.1	cAMP-activated global transcriptional regulator CRP	Regulator
B7L42_RS12090 (B7L42_12090)	-	2408842..2409932 (+)	1091	WP_085940413.1	IS4-like element ISAba1 family transposase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 24956.78 Da
• Isoelectric Point: 8.1128

>NTDB_id=224606 B7L42_RS12085 WP_000203219.1 2408120..2408785(+) (crp) [Acinetobacter baumannii strain 15A34]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFLCTR

Nucleotide

• Length: 666 bp

>NTDB_id=224606 B7L42_RS12085 WP_000203219.1 2408120..2408785(+) (crp) [Acinetobacter baumannii strain 15A34]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCGGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGCCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTCTCTGTACACGATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, crp family (Crp) (176-207)

• Cyclic nucleotide-binding domain (cNMP_binding) (33-120)

3D structure

• AlphaFold DB: A0A219CAS9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Acinetobacter baumannii D1279779	100	98.19	0.982
crp	Vibrio cholerae strain A1552	47.317	92.76	0.439
crp	Haemophilus influenzae Rd KW20	48.705	87.33	0.425