Detailed information NTG0022460

Bioinformatically predicted

Overview

• Name: ruvA
• Type: Machinery gene
• Locus tag: NMA_RS11315
• Genome accession: NC_003116
• Coordinates: 2174247..2174831 (+)
• Length: 194 a.a.
• NCBI ID: WP_002240238.1
• Uniprot ID: Q9JSM5
• Organism: Neisseria meningitidis Z2491
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2169247..2179831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMA_RS14750 (NMA2214)	-	2169450..2170076 (-)	627	WP_010981296.1	hypothetical protein	-
NMA_RS14755 (NMA2215)	-	2170152..2170940 (-)	789	WP_002245837.1	class I SAM-dependent methyltransferase	-
NMA_RS14760 (NMA2216)	bioH	2170945..2171685 (-)	741	Protein_2120	pimeloyl-ACP methyl ester esterase BioH	-
NMA_RS11295 (NMA2217)	-	2171684..2172409 (+)	726	WP_002228923.1	ComF family protein	-
NMA_RS11300 (NMA2218)	trmL	2172474..2172938 (+)	465	WP_002215661.1	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	-
NMA_RS11305 (NMA2219)	-	2173066..2173785 (+)	720	WP_002245836.1	septal ring lytic transglycosylase RlpA family protein	-
NMA_RS11310 (NMA2220)	-	2173839..2174165 (+)	327	WP_002218661.1	PepSY domain-containing protein	-
NMA_RS11315 (NMA2221)	ruvA	2174247..2174831 (+)	585	WP_002240238.1	Holliday junction branch migration protein RuvA	Machinery gene
NMA_RS14370	-	2174831..2174968 (+)	138	WP_002240237.1	hypothetical protein	-
NMA_RS11325 (NMA2223)	-	2174994..2176850 (+)	1857	WP_002245835.1	ABC transporter ATP-binding protein	-
NMA_RS11330 (NMA2224)	rsgA	2176855..2177778 (+)	924	WP_002226945.1	ribosome small subunit-dependent GTPase A	-
NMA_RS11335 (NMA2225)	-	2178042..2178266 (+)	225	WP_002246752.1	exodeoxyribonuclease VII small subunit	-
NMA_RS11340 (NMA2226)	-	2178250..2179146 (+)	897	WP_002245834.1	polyprenyl synthetase family protein	-
NMA_RS11345 (NMA2227)	-	2179255..2179554 (-)	300	WP_002226942.1	DUF2818 family protein	-

Sequence

Protein

• Length: 194 a.a.
• Molecular weight: 20599.80 Da
• Isoelectric Point: 5.1063

>NTDB_id=22460 NMA_RS11315 WP_002240238.1 2174247..2174831(+) (ruvA) [Neisseria meningitidis Z2491]
MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGG
IGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHAVTDGLFAAAPAADETEDIVGTLLA
LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK

Nucleotide

• Length: 585 bp

>NTDB_id=22460 NMA_RS11315 WP_002240238.1 2174247..2174831(+) (ruvA) [Neisseria meningitidis Z2491]
ATGATCAGCAGACTGACCGGCAAACTGGTTGAAAAAAACCCTCCGCAAATCGTCATCGATGTCAACGGTGTCGGCTATGA
GGCCGACGTATCGATGCAGACCTTCTACAACCTGCCGCCCGTGGGTGAAAGCGTACAACTGTTTACCCAGCTTATCATTC
GGGAAGACGCACATCTTTTATTTGGTTTTGCCACTGCGGAAGAACGCAAAACATTCCGCCAACTGATCAAGGTCGGCGGC
ATCGGCGCGAAAACGGCTTTGGGCATTTTGTCGGCGATGACGGCAGACGAGCTGGCGCAGGCGGTTGCAGAAGAAGATGT
CAAACGCCTCTCCTCCGCCCCGGGAATCGGCAAAAAAACCGCCGAACGCATGGTTTTGGAACTGCGCGGCAAGCTGGTCG
CGCATGCGGTAACGGACGGGCTGTTTGCCGCCGCACCCGCCGCCGACGAAACGGAAGACATCGTCGGCACGCTGCTTGCG
CTGGGTTACAGCGAACGCGAAGCAAAAGCGGCGGTCAAAGGCGTTCCGGAGGGGACGGACGTGGGCGAAGGCGTGCGCCT
TGCTTTGAAAAACCTGCTGAAATAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix domain (HHH_5) (72-129)

• RuvA N terminal domain (RuvA_N) (1-62)

• RuvA, C-terminal domain (RuvA_C) (150-192)

3D structure

• AlphaFold DB: Q9JSM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvA	Streptococcus pneumoniae R6	38	100	0.392
ruvA	Streptococcus pneumoniae D39	38	100	0.392
ruvA	Streptococcus pneumoniae TIGR4	37.5	100	0.387
ruvA	Bacillus subtilis subsp. subtilis str. 168	35.922	100	0.381