Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   NMA_RS07710 Genome accession   NC_003116
Coordinates   1441083..1443110 (-) Length   675 a.a.
NCBI ID   WP_002245989.1    Uniprot ID   P56996
Organism   Neisseria meningitidis Z2491     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1436083..1448110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA_RS07690 (NMA1541) - 1437040..1438443 (+) 1404 WP_002227257.1 tetratricopeptide repeat protein -
  NMA_RS07695 (NMA1542) trmB 1438565..1439281 (+) 717 WP_002227255.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  NMA_RS07700 (NMA1543) - 1439500..1440152 (+) 653 Protein_1459 IS1595 family transposase -
  NMA_RS07705 (NMA1544) - 1440251..1441015 (-) 765 WP_002245990.1 KilA-N domain-containing protein -
  NMA_RS07710 (NMA1545) uvrB 1441083..1443110 (-) 2028 WP_002245989.1 excinuclease ABC subunit UvrB Machinery gene
  NMA_RS13855 - 1443283..1443429 (-) 147 WP_153308396.1 hypothetical protein -
  NMA_RS07715 (NMA1546) - 1443439..1444923 (-) 1485 WP_002226303.1 S41 family peptidase -
  NMA_RS07720 (NMA1547) - 1445043..1446848 (-) 1806 WP_002227254.1 murein hydrolase activator EnvC family protein -
  NMA_RS07730 (NMA1549) - 1447176..1447736 (+) 561 WP_002219151.1 CreA family protein -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 76936.38 Da        Isoelectric Point: 5.0455

>NTDB_id=22438 NMA_RS07710 WP_002245989.1 1441083..1443110(-) (uvrB) [Neisseria meningitidis Z2491]
MEVIRYPDSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
HQRVGRYTVFPSSHYVTPRDTVLRACDSIKEELRERIDFFTKENRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPSNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAIDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKL
EKAMQQAARDLQFEEAAVLRDRIRNIKENLLFGAE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=22438 NMA_RS07710 WP_002245989.1 1441083..1443110(-) (uvrB) [Neisseria meningitidis Z2491]
ATGGAAGTCATCCGATACCCCGATTCCCCTTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCTACCGCTAT
TGCCGGCTTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CCATGGCGAACGTCATCGCCCAAAGCGGCCGACCCGCCATCATCATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCTGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTATTACCAACCCGAAGCCTA
TGTGCCCAGCCGCGACCTGTTCATTGAAAAAGACAGCGCGATCAACGAACATATCGAGCAGATGCGCCTTTCCGCCACCA
AAAACCTGATGACGCGCGATGACGTGATTATCGTTGCCACTGTGTCCGCCATTTACGGTATCGGCGACCCGACTGAGTAT
CAACAAATGGTGTTGTCCGTCAAAGAAGGCGACACCATCGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAACGCGGCGATTTGGATTTCAAACGCGGCAGCTTCCGCGTGCGCGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGCATCAGCCTGTTTGACGACGAAATCGACCGCCTCGATATGTTCGACCCGCTTTCAGGCAGCCTG
CACCAACGCGTCGGCCGCTACACCGTCTTCCCGTCCAGCCACTACGTTACCCCGCGCGACACCGTATTGCGCGCCTGTGA
CTCCATCAAAGAAGAATTGCGCGAACGCATTGATTTCTTTACCAAAGAAAACCGTCCCGTCGAACAACAACGCATCGAAC
AGCGCACCCGCTTCGACCTCGAAATGCTCTACGAAATGGGCTTCTGTAAAGGAATCGAAAACTACTCCCGCCACTTCTCC
GGCAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCAAGCAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTAACCCAAATCGGCGGTATGTACAAAGGCGACGCATCGCGCAAGCAAAACCTCGTCGATTACGGCTTCCGCC
TGCCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCACGAATTTGAAAAAGTCATGCCGCAAACCGTCTTCGTTTCCGCC
ACCCCCGCCAAATACGAAGAAGAACACGCCGGACAAGTGGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCTCA
AATCATCATCCGCCCCGTCGCCACCCAAGTCGACGATTTAATGAGCGAAATCAACGACCGCATCCAAAAAGGCGAACGCG
TACTCGTTACCACCCTTACCAAACGCATGGCGGAGCAACTCACCGACTATTACAGCGAACTCGGCATCAAAGTGCGCTAC
CTGCACAGCGACATCGACACCGTAGAGCGCGTTGAAATTATTAGAGATTTACGGCTCGGATTGTTTGACGTACTCGTCGG
CATCAATCTCTTGCGCGAAGGCCTCGACATCCCAGAAGTCTCCCTCGTCGCCATCCTCGACGCAGACAAAGAAGGCTTCC
TGCGCTCCCACCGCAGCCTGATTCAAACCATAGGCCGCGCTGCGCGCAACGTGAACGGCGTCGCGATTCTGTACGCCGAC
AAAATCACCGACTCTATGAAAGCCGCCATCGACGAAACCGAACGCCGCCGTGAAAAACAAATTAAATTCAACGAAGAACA
CGGCATCGTGCCGCAACAGATTAAAAAACAGGTCAAAGACATCATTGACGGCGTGTACCACGAAGAAGACAGCGGCAAAG
GCCGTAGACAAGGCAAAAACAAAGTTAAAGTCGGCGAAATTCACAACGAAGAAGACGCGATTAAAGAAATCGCCAAACTC
GAAAAAGCCATGCAACAGGCGGCTAGGGATTTGCAGTTTGAAGAAGCGGCGGTGTTGAGGGATAGGATTAGGAATATTAA
AGAGAATTTGTTGTTTGGGGCAGAGTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Type III restriction enzyme, res subunit (ResIII)

(23-144)

UvrB/uvrC motif (UVR)

(635-668)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

UvrB interaction domain (UvrB_inter)

(165-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P56996

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.505

98.222

0.545
  uvrB Streptococcus pneumoniae R6

55.505

98.222

0.545
  uvrB Streptococcus pneumoniae D39

55.505

98.222

0.545

Multiple sequence alignment