Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | B4U56_RS08980 | Genome accession | NZ_CP020463 |
| Coordinates | 1835122..1835697 (-) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain 1457 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1794046..1834721 | 1835122..1835697 | flank | 401 |
Gene organization within MGE regions
Location: 1794046..1835697
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B4U56_RS08710 (B4U56_08705) | - | 1794046..1795509 (-) | 1464 | WP_032606340.1 | SH3 domain-containing protein | - |
| B4U56_RS08715 (B4U56_08710) | - | 1795484..1795894 (-) | 411 | WP_002502079.1 | phage holin | - |
| B4U56_RS08720 (B4U56_08715) | - | 1795958..1796356 (-) | 399 | WP_032606342.1 | YxeA family protein | - |
| B4U56_RS08725 (B4U56_08720) | - | 1796514..1796921 (-) | 408 | WP_002502077.1 | hypothetical protein | - |
| B4U56_RS08730 (B4U56_08725) | - | 1796908..1797333 (-) | 426 | WP_002502076.1 | hypothetical protein | - |
| B4U56_RS08735 (B4U56_08730) | - | 1797330..1797953 (-) | 624 | WP_032606043.1 | poly-gamma-glutamate hydrolase family protein | - |
| B4U56_RS08740 (B4U56_08735) | - | 1797958..1799172 (-) | 1215 | WP_002502074.1 | BppU family phage baseplate upper protein | - |
| B4U56_RS08745 (B4U56_08740) | - | 1799172..1801034 (-) | 1863 | WP_002502073.1 | M14 family metallopeptidase | - |
| B4U56_RS12500 | - | 1801050..1801223 (-) | 174 | WP_002502072.1 | hypothetical protein | - |
| B4U56_RS08750 (B4U56_08745) | - | 1801216..1802775 (-) | 1560 | WP_002502071.1 | prophage endopeptidase tail family protein | - |
| B4U56_RS08755 (B4U56_08750) | - | 1802785..1803618 (-) | 834 | WP_002502070.1 | phage tail domain-containing protein | - |
| B4U56_RS08760 (B4U56_08755) | - | 1803620..1808331 (-) | 4712 | Protein_1623 | phage tail tape measure protein | - |
| B4U56_RS12405 | gpGT | 1808360..1808512 (-) | 153 | WP_002502068.1 | phage tail assembly chaperone GT | - |
| B4U56_RS08765 (B4U56_08760) | gpG | 1808545..1808907 (-) | 363 | WP_002502067.1 | phage tail assembly chaperone G | - |
| B4U56_RS08770 (B4U56_08765) | - | 1808971..1809156 (-) | 186 | WP_002502066.1 | hypothetical protein | - |
| B4U56_RS08775 (B4U56_08770) | - | 1809175..1809801 (-) | 627 | WP_002502065.1 | major tail protein | - |
| B4U56_RS08780 (B4U56_08775) | - | 1809814..1810218 (-) | 405 | WP_002502064.1 | hypothetical protein | - |
| B4U56_RS08785 (B4U56_08780) | - | 1810221..1810487 (-) | 267 | WP_002502063.1 | hypothetical protein | - |
| B4U56_RS08790 (B4U56_08785) | - | 1810622..1810951 (-) | 330 | WP_002502062.1 | head-tail adaptor protein | - |
| B4U56_RS08795 (B4U56_08790) | - | 1810941..1811282 (-) | 342 | WP_002502061.1 | head-tail connector protein | - |
| B4U56_RS08800 (B4U56_08795) | - | 1811301..1812626 (-) | 1326 | WP_002502060.1 | phage major capsid protein | - |
| B4U56_RS08805 (B4U56_08800) | - | 1812668..1813225 (-) | 558 | WP_002497603.1 | HK97 family phage prohead protease | - |
| B4U56_RS08810 (B4U56_08805) | - | 1813215..1814447 (-) | 1233 | WP_002502059.1 | phage portal protein | - |
| B4U56_RS12755 (B4U56_08810) | - | 1814447..1814641 (-) | 195 | WP_002502058.1 | hypothetical protein | - |
| B4U56_RS08820 (B4U56_08815) | - | 1814657..1816408 (-) | 1752 | WP_002502057.1 | terminase large subunit | - |
| B4U56_RS08825 (B4U56_08820) | - | 1816401..1816886 (-) | 486 | WP_002502056.1 | phage terminase small subunit P27 family | - |
| B4U56_RS08830 (B4U56_08825) | - | 1817046..1817396 (-) | 351 | WP_002502055.1 | HNH endonuclease | - |
| B4U56_RS08835 (B4U56_08830) | - | 1817879..1818325 (-) | 447 | WP_002502054.1 | transcriptional regulator | - |
| B4U56_RS12645 | - | 1818342..1818491 (-) | 150 | WP_002502053.1 | DUF1514 domain-containing protein | - |
| B4U56_RS08840 (B4U56_08835) | rinB | 1818492..1818674 (-) | 183 | WP_002502052.1 | transcriptional activator RinB | - |
| B4U56_RS08845 (B4U56_08840) | - | 1818779..1819081 (+) | 303 | WP_002499245.1 | DUF4870 domain-containing protein | - |
| B4U56_RS08850 (B4U56_08845) | dut | 1819178..1819603 (-) | 426 | WP_002502051.1 | dUTP diphosphatase | - |
| B4U56_RS12705 | - | 1819596..1819721 (-) | 126 | WP_002502050.1 | hypothetical protein | - |
| B4U56_RS08855 (B4U56_08850) | - | 1819723..1820130 (-) | 408 | WP_002502049.1 | RusA family crossover junction endodeoxyribonuclease | - |
| B4U56_RS08860 (B4U56_08855) | - | 1820140..1820367 (-) | 228 | WP_002502048.1 | DUF3269 family protein | - |
| B4U56_RS08865 (B4U56_08860) | - | 1820386..1821267 (-) | 882 | WP_232755969.1 | DnaD domain-containing protein | - |
| B4U56_RS08870 (B4U56_08865) | ssbA | 1821374..1821841 (-) | 468 | WP_002502046.1 | single-stranded DNA-binding protein | Machinery gene |
| B4U56_RS08875 (B4U56_08870) | - | 1821842..1822471 (-) | 630 | WP_256280252.1 | MBL fold metallo-hydrolase | - |
| B4U56_RS08880 (B4U56_08875) | - | 1822540..1823475 (-) | 936 | WP_032606345.1 | recombinase RecT | - |
| B4U56_RS08885 (B4U56_08880) | - | 1823477..1825426 (-) | 1950 | WP_002502043.1 | AAA family ATPase | - |
| B4U56_RS08890 (B4U56_08885) | - | 1825429..1825692 (-) | 264 | WP_002502042.1 | hypothetical protein | - |
| B4U56_RS08895 (B4U56_08890) | - | 1825752..1825943 (-) | 192 | WP_002502041.1 | DUF1270 family protein | - |
| B4U56_RS08900 (B4U56_08895) | - | 1826033..1826314 (+) | 282 | WP_002502040.1 | hypothetical protein | - |
| B4U56_RS12505 | - | 1826311..1826457 (-) | 147 | WP_002502039.1 | hypothetical protein | - |
| B4U56_RS08905 (B4U56_08900) | - | 1826473..1826682 (-) | 210 | WP_002502038.1 | hypothetical protein | - |
| B4U56_RS08910 (B4U56_08905) | - | 1826740..1827078 (+) | 339 | WP_002499261.1 | hypothetical protein | - |
| B4U56_RS08915 (B4U56_08910) | - | 1827064..1827296 (-) | 233 | Protein_1658 | MW1434 family type I TA system toxin | - |
| B4U56_RS08920 (B4U56_08915) | - | 1827383..1827595 (+) | 213 | WP_002499263.1 | hypothetical protein | - |
| B4U56_RS12650 | - | 1827601..1827687 (-) | 87 | Protein_1660 | hypothetical protein | - |
| B4U56_RS08925 (B4U56_08920) | - | 1827729..1828475 (-) | 747 | WP_002502037.1 | phage antirepressor KilAC domain-containing protein | - |
| B4U56_RS08930 (B4U56_08925) | - | 1828526..1829080 (+) | 555 | WP_002502036.1 | hypothetical protein | - |
| B4U56_RS12510 | - | 1829087..1829224 (-) | 138 | WP_002502035.1 | hypothetical protein | - |
| B4U56_RS08935 (B4U56_08930) | - | 1829262..1829501 (-) | 240 | WP_002499267.1 | helix-turn-helix transcriptional regulator | - |
| B4U56_RS08940 (B4U56_08935) | - | 1829642..1830262 (+) | 621 | WP_002499268.1 | LexA family protein | - |
| B4U56_RS12515 | - | 1830307..1830474 (+) | 168 | WP_002502034.1 | hypothetical protein | - |
| B4U56_RS08945 (B4U56_08940) | - | 1830496..1831635 (+) | 1140 | WP_080280816.1 | CapA family protein | - |
| B4U56_RS08950 (B4U56_08945) | - | 1831844..1832428 (+) | 585 | WP_032606347.1 | hypothetical protein | - |
| B4U56_RS08955 (B4U56_08950) | - | 1832497..1833387 (+) | 891 | WP_032606348.1 | hypothetical protein | - |
| B4U56_RS08960 (B4U56_08955) | - | 1833398..1833577 (-) | 180 | WP_032606349.1 | hypothetical protein | - |
| B4U56_RS08965 (B4U56_08960) | - | 1833672..1834721 (+) | 1050 | WP_032606350.1 | tyrosine-type recombinase/integrase | - |
| B4U56_RS08980 (B4U56_08975) | comK/comK1 | 1835122..1835697 (-) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=223405 B4U56_RS08980 WP_001829272.1 1835122..1835697(-) (comK/comK1) [Staphylococcus epidermidis strain 1457]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=223405 B4U56_RS08980 WP_001829272.1 1835122..1835697(-) (comK/comK1) [Staphylococcus epidermidis strain 1457]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |