Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   RK77_RS12745 Genome accession   NZ_CP026064
Coordinates   2471658..2472647 (+) Length   329 a.a.
NCBI ID   WP_000219066.1    Uniprot ID   P67655
Organism   Staphylococcus aureus strain FDAARGOS_19     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2466658..2477647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RK77_RS12720 (RK77_012720) - 2467411..2467902 (+) 492 WP_000383814.1 DUF948 domain-containing protein -
  RK77_RS12725 (RK77_012725) - 2467976..2469334 (+) 1359 WP_000193930.1 hypothetical protein -
  RK77_RS12730 (RK77_012730) - 2469490..2469573 (+) 84 WP_031789490.1 hypothetical protein -
  RK77_RS12735 (RK77_012735) - 2470028..2471119 (+) 1092 WP_000066379.1 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase -
  RK77_RS12740 (RK77_012740) - 2471472..2471585 (+) 114 WP_001788994.1 hypothetical protein -
  RK77_RS12745 (RK77_012745) ccpA 2471658..2472647 (+) 990 WP_000219066.1 catabolite control protein A Regulator
  RK77_RS12750 (RK77_012750) - 2472745..2473914 (-) 1170 WP_001184003.1 acetoin utilization protein AcuC -
  RK77_RS12755 (RK77_012755) - 2473939..2474571 (-) 633 WP_001016007.1 GNAT family N-acetyltransferase -
  RK77_RS12760 (RK77_012760) acsA 2474740..2476446 (+) 1707 WP_000862105.1 acetate--CoA ligase -

Sequence

Protein


Download         Length: 329 a.a.        Molecular weight: 36060.24 Da        Isoelectric Point: 5.5054

>NTDB_id=223283 RK77_RS12745 WP_000219066.1 2471658..2472647(+) (ccpA) [Staphylococcus aureus strain FDAARGOS_19]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide


Download         Length: 990 bp        

>NTDB_id=223283 RK77_RS12745 WP_000219066.1 2471658..2472647(+) (ccpA) [Staphylococcus aureus strain FDAARGOS_19]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAAGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGTCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGTAATCTTCCAGATGCTATA
TTATGTATTAGTGACGAAGAAGCTATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGTTTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAATGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, lacI family (LacI)

(4-49)

Periplasmic binding protein-like domain (Peripla_BP_3)

(171-328)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P67655

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

47.879

100

0.48
  ccpA Streptococcus gordonii str. Challis substr. CH1

47.112

100

0.471
  ccpA Streptococcus pneumoniae D39

46.201

100

0.462