Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A6J87_RS03000 Genome accession   NZ_CP020451
Coordinates   608998..610317 (-) Length   439 a.a.
NCBI ID   WP_080611551.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 598749..610317 608998..610317 within 0


Gene organization within MGE regions


Location: 598749..610317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS02920 (A6J87_02905) recX 598749..599525 (+) 777 WP_070576620.1 recombination regulator RecX -
  A6J87_RS02925 (A6J87_02910) - 599596..600129 (+) 534 WP_002886644.1 DUF402 domain-containing protein -
  A6J87_RS02930 (A6J87_02915) - 600159..600818 (-) 660 WP_080611549.1 DUF1803 domain-containing protein -
  A6J87_RS02935 (A6J87_02920) - 600873..601805 (-) 933 WP_070576625.1 manganese-dependent inorganic pyrophosphatase -
  A6J87_RS02990 (A6J87_02975) hpf 607728..608276 (-) 549 WP_080611550.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  A6J87_RS02995 (A6J87_02980) - 608355..609017 (-) 663 WP_002883740.1 ComF family protein -
  A6J87_RS03000 (A6J87_02985) comFA/cflA 608998..610317 (-) 1320 WP_080611551.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50645.62 Da        Isoelectric Point: 8.9020

>NTDB_id=223231 A6J87_RS03000 WP_080611551.1 608998..610317(-) (comFA/cflA) [Streptococcus salivarius strain FDAARGOS_259]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKKLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGSLEKHHLARRFHGNPLVLPKFCWQGRLQKSLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQNYLPDEKMAFVSSKSEERSATVENFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=223231 A6J87_RS03000 WP_080611551.1 608998..610317(-) (comFA/cflA) [Streptococcus salivarius strain FDAARGOS_259]
ATGGTACCTAAAGAATATTATGGACGGCTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAAAAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCAGAAATTGAGTTTCCTGTTTTGAAGTGGTTGGGAGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGATCTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTCACTAGCATT
CTACAAAACTATCTTCCAGATGAAAAAATGGCCTTTGTTTCCTCAAAAAGTGAGGAGCGTTCAGCTACCGTAGAGAACTT
CCGAGAAAAAGAGTTATCCATTTTAGTGACAACAACTATCCTCGAACGTGGTGTGACCTTTCCACAAGTAGATGTTTTTG
TTTGCATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCTCCAGATAGA
CCGACAGGGAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae D39

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae R6

56.613

98.178

0.556
  comFA/cflA Streptococcus pneumoniae TIGR4

56.613

98.178

0.556
  comFA/cflA Streptococcus mitis NCTC 12261

55.76

98.861

0.551
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.714

95.672

0.437
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376

Multiple sequence alignment