Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   A6J31_RS09430 Genome accession   NZ_CP020431
Coordinates   1831288..1832523 (+) Length   411 a.a.
NCBI ID   WP_013991347.1    Uniprot ID   A0AB37CMH1
Organism   Streptococcus sp. FDAARGOS_192     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1826288..1837523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS09400 (A6J31_09340) - 1826761..1829355 (+) 2595 WP_080611038.1 YfhO family protein -
  A6J31_RS09420 (A6J31_09360) - 1829904..1830587 (-) 684 WP_002883977.1 YoaK family protein -
  A6J31_RS09425 (A6J31_09365) rlmH 1830603..1831082 (-) 480 WP_080611040.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  A6J31_RS09430 (A6J31_09370) htrA 1831288..1832523 (+) 1236 WP_013991347.1 S1C family serine protease Regulator
  A6J31_RS09435 (A6J31_09375) spo0J 1832589..1833356 (+) 768 WP_014635206.1 ParB/RepB/Spo0J family partition protein Regulator
  A6J31_RS09445 (A6J31_09385) dnaA 1833595..1834959 (+) 1365 WP_049553505.1 chromosomal replication initiator protein DnaA -
  A6J31_RS09450 (A6J31_09390) dnaN 1835114..1836250 (+) 1137 WP_080611042.1 DNA polymerase III subunit beta -
  A6J31_RS09455 (A6J31_09395) - 1836302..1836493 (+) 192 WP_037599384.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 42915.09 Da        Isoelectric Point: 4.6266

>NTDB_id=222901 A6J31_RS09430 WP_013991347.1 1831288..1832523(+) (htrA) [Streptococcus sp. FDAARGOS_192]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=222901 A6J31_RS09430 WP_013991347.1 1831288..1832523(+) (htrA) [Streptococcus sp. FDAARGOS_192]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTAGGTGGTTTACTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTGCAAGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGGAAAGAGGCCTACATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCAGAATTTGCAGACTC
AAACTCTCTCACAGTCGGCGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATATGCCAACTCAGTAACAGAGG
GTATCGTTTCTAGCCTTAGCCGTACTGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATTCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAGA
TTATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAATAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(7-406)

Trypsin-like peptidase domain (Trypsin_2)

(118-263)

PDZ domain (PDZ_2)

(307-402)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.787

98.054

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.389

98.783

0.567
  htrA Streptococcus pneumoniae Rx1

54.279

99.513

0.54
  htrA Streptococcus pneumoniae R6

54.279

99.513

0.54
  htrA Streptococcus pneumoniae TIGR4

54.279

99.513

0.54
  htrA Streptococcus pneumoniae D39

54.279

99.513

0.54
  htrA Streptococcus mitis NCTC 12261

54.279

99.513

0.54

Multiple sequence alignment