Detailed information NTG0222812

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: A6J30_RS03915
• Genome accession: NZ_CP020427
• Coordinates: 845005..847263 (-)
• Length: 752 a.a.
• NCBI ID: WP_005481856.1
• Uniprot ID: Q87R17
• Organism: Vibrio parahaemolyticus strain FDAARGOS_191
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	825353..849940	845005..847263	within	0

Gene organization within MGE regions

Location: 825353..849940

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J30_RS03830 (A6J30_03715)	-	825353..826123 (-)	771	WP_005456207.1	ABC transporter ATP-binding protein	-
A6J30_RS03840 (A6J30_03720)	-	826358..827818 (-)	1461	WP_005481901.1	flagellar sheath protein A	-
A6J30_RS03845 (A6J30_03725)	-	828275..829822 (+)	1548	WP_005456280.1	DUF3360 family protein	-
A6J30_RS03850 (A6J30_03730)	pflB	830129..832405 (+)	2277	WP_005456189.1	formate C-acetyltransferase	-
A6J30_RS03855 (A6J30_03735)	-	832558..833535 (+)	978	WP_005481800.1	lipid A deacylase LpxR family protein	-
A6J30_RS03860 (A6J30_03740)	pflA	833682..834422 (+)	741	WP_005456250.1	pyruvate formate lyase 1-activating protein	-
A6J30_RS03865 (A6J30_03745)	-	834583..835251 (+)	669	WP_005481831.1	energy-coupling factor ABC transporter permease	-
A6J30_RS03870 (A6J30_03750)	-	835406..835906 (+)	501	WP_005456271.1	YfbU family protein	-
A6J30_RS03880 (A6J30_03755)	-	836395..838329 (+)	1935	WP_005456210.1	PrkA family serine protein kinase	-
A6J30_RS03885 (A6J30_03760)	-	838377..839648 (+)	1272	WP_005481863.1	YeaH/YhbH family protein	-
A6J30_RS03890 (A6J30_03765)	-	839660..841219 (+)	1560	WP_005456192.1	SpoVR family protein	-
A6J30_RS03895 (A6J30_03770)	kdsB	841297..842052 (-)	756	WP_005456221.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
A6J30_RS03900 (A6J30_03775)	-	842052..842231 (-)	180	WP_005378451.1	Trm112 family protein	-
A6J30_RS03905 (A6J30_03780)	lpxK	842212..843219 (-)	1008	WP_005456276.1	tetraacyldisaccharide 4'-kinase	-
A6J30_RS03910 (A6J30_03785)	msbA	843225..844973 (-)	1749	WP_005456206.1	lipid A ABC transporter ATP-binding protein/permease MsbA	-
A6J30_RS03915 (A6J30_03790)	comEC	845005..847263 (-)	2259	WP_005481856.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6J30_RS03920 (A6J30_03795)	-	847272..847781 (+)	510	WP_005481854.1	DUF2062 domain-containing protein	-
A6J30_RS03925 (A6J30_03800)	lolE	847986..849230 (-)	1245	WP_005481897.1	lipoprotein-releasing ABC transporter permease subunit LolE	-
A6J30_RS03930 (A6J30_03805)	lolD	849233..849940 (-)	708	WP_005481886.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 84699.17 Da
• Isoelectric Point: 9.5661

>NTDB_id=222812 A6J30_RS03915 WP_005481856.1 845005..847263(-) (comEC) [Vibrio parahaemolyticus strain FDAARGOS_191]
MTLLEKSWTLALFVASVISSAWWPTMPDWRWLLLGIITTGSIIKLRRGLISIGVIVGFMVVIVHGNIMEYQRQALFQAGE
NSTIIGRVDSSFTQISHGYEGVVAIKQVNSHTLLPFLKPKVRLITPFPLAVNSEFTTNVLIKPIIGLRNEAGFDAEKQSM
GSGVVARAVVTKDSYWVIRTSSSWREAIIQTVERDISRLEHFALIKALAFADRTGLTKEDWQSLRDSGLLHLVSISGLHI
GMALTFGLALGGLIRLAMPRYWFLPSVSGLAFAIVYAWLADFSLPTTRAVSVCIIYIALKYWLVHWSPWRVLLLAVALQL
FFQPFASFSLSFWLSYLSVGAVLFAVNTVQDSKEGRLGKLRILLLTQLILSLLIVPISGYFFSGFSWSSLVYNLVFIPWF
GFVVVPIMFAALIASLLFPMLATVLWYLLDIFLVPLSWSVRYAIGTWQPISAEWTFVIAVVSAVLVSRHVMPRYVWMFVC
VIVVMTGLFPKQYNQTWRIDVLDVGHGLAVLVEKEGRVLLYDTGKAWQNGSIAEQVITPVLHRRGYSSVDTMILSHADND
HAGGRKVIEQYFSPKHKLSSQSFLHYQPCIAAEKWKWQGLNMEVLWPPKPVVRAYNPHSCVISLEDPSTGFKMLFTGDIE
AISEWILLREPEKLRSDVMLVPHHGSKSSSNPKFINVVEPSLAIASTAKLNQWGMPAPEVVQAYTDSGVSWLDTGSDGQI
TILLDGNNWRFESKRRETIEPWYRQMLRNRVE

Nucleotide

• Length: 2259 bp

>NTDB_id=222812 A6J30_RS03915 WP_005481856.1 845005..847263(-) (comEC) [Vibrio parahaemolyticus strain FDAARGOS_191]
ATGACTCTCTTAGAAAAAAGTTGGACCTTGGCGTTATTTGTCGCGAGCGTAATTTCGTCTGCATGGTGGCCGACGATGCC
GGATTGGCGTTGGTTGCTGCTGGGAATAATTACCACTGGCTCAATAATTAAATTACGTCGAGGCTTAATTAGCATAGGCG
TAATTGTGGGCTTTATGGTTGTCATCGTCCACGGCAATATTATGGAGTATCAGAGACAAGCCCTTTTTCAAGCAGGTGAG
AATAGTACCATAATTGGTAGAGTTGACAGCTCTTTTACGCAAATAAGTCACGGATATGAAGGTGTCGTAGCGATAAAACA
AGTGAATTCTCACACTCTGTTACCTTTTCTTAAACCTAAAGTCCGCCTTATAACGCCATTCCCACTAGCTGTTAACAGTG
AGTTTACGACTAACGTTTTGATTAAGCCCATTATCGGCCTCAGAAATGAAGCGGGTTTCGACGCAGAAAAGCAGTCAATG
GGAAGTGGTGTTGTTGCAAGGGCGGTCGTTACTAAAGATTCATACTGGGTCATTCGTACTTCTTCGTCTTGGCGCGAAGC
TATTATTCAAACTGTTGAGCGTGATATTTCTCGCCTTGAGCATTTTGCTCTAATCAAAGCACTGGCTTTTGCTGATCGCA
CTGGGCTTACCAAAGAGGATTGGCAGTCTCTGCGTGACAGCGGACTACTGCATCTTGTATCGATTTCTGGTTTACACATT
GGGATGGCACTGACGTTTGGGCTCGCCCTTGGTGGGCTTATTCGGCTTGCTATGCCGCGATATTGGTTTCTGCCATCAGT
TAGTGGGTTGGCGTTTGCCATTGTTTACGCTTGGCTTGCTGATTTTTCTTTGCCGACGACCCGAGCCGTTTCTGTTTGTA
TCATCTATATTGCTTTGAAGTATTGGCTTGTTCATTGGAGCCCATGGCGCGTACTGTTACTGGCCGTGGCATTGCAACTT
TTCTTCCAACCTTTTGCTTCTTTTAGTTTGAGTTTTTGGCTGTCTTATTTATCCGTTGGTGCCGTTTTGTTTGCGGTTAA
CACAGTGCAAGACTCGAAGGAAGGTCGTTTGGGAAAGTTGCGGATACTTCTGTTGACTCAACTGATACTGAGCTTATTGA
TTGTCCCGATCAGTGGCTATTTTTTCTCTGGATTTAGCTGGTCTTCTTTAGTCTACAATTTGGTTTTCATTCCTTGGTTT
GGCTTTGTTGTCGTTCCAATCATGTTTGCTGCTTTAATTGCGTCATTGCTCTTTCCTATGTTGGCGACGGTCCTATGGTA
TTTGCTTGACATATTCCTGGTTCCACTAAGTTGGTCGGTTCGATATGCCATAGGAACTTGGCAACCCATTAGTGCCGAGT
GGACATTTGTTATTGCTGTAGTGAGTGCCGTGCTCGTTTCAAGACATGTTATGCCTCGTTACGTTTGGATGTTTGTCTGT
GTAATTGTTGTGATGACCGGGTTGTTTCCTAAGCAATATAACCAAACTTGGCGTATTGATGTGCTTGATGTCGGGCATGG
GTTGGCGGTGCTGGTCGAAAAAGAAGGGAGAGTTTTACTCTATGATACGGGCAAGGCTTGGCAAAACGGCAGTATAGCTG
AGCAAGTGATTACGCCAGTACTGCACCGCAGAGGTTACTCAAGTGTCGATACGATGATTTTAAGTCATGCTGATAATGAC
CATGCTGGTGGCCGAAAAGTGATAGAACAGTACTTTTCACCTAAACACAAACTAAGCAGCCAGAGCTTTTTACATTATCA
GCCTTGTATTGCTGCTGAGAAATGGAAGTGGCAAGGGTTGAACATGGAGGTACTTTGGCCTCCTAAACCTGTAGTACGAG
CATACAACCCCCACTCTTGTGTCATCAGTCTGGAAGACCCTAGTACAGGTTTTAAAATGTTGTTTACTGGTGATATCGAA
GCCATCAGCGAATGGATACTGCTTCGAGAGCCAGAAAAGCTGCGCAGTGATGTAATGCTAGTGCCGCATCATGGAAGCAA
AAGCTCTTCTAACCCTAAGTTTATCAATGTTGTTGAGCCTAGCTTGGCTATTGCTTCAACGGCAAAACTAAACCAGTGGG
GAATGCCCGCACCTGAAGTCGTTCAAGCCTATACCGACAGTGGTGTTAGTTGGTTAGACACTGGAAGTGATGGCCAAATA
ACAATCTTACTTGATGGCAATAACTGGCGTTTTGAAAGTAAACGTCGTGAGACAATTGAGCCTTGGTATAGGCAGATGCT
GCGTAACCGAGTAGAATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (504-677)

3D structure

• AlphaFold DB: Q87R17

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Vibrio parahaemolyticus RIMD 2210633	100	100	1
comEC	Vibrio campbellii strain DS40M4	66.755	100	0.668
comEC	Vibrio cholerae strain A1552	41.215	100	0.415