Detailed information NTG0022278

Bioinformatically predicted

Overview

• Name: pptB
• Type: Regulator
• Locus tag: SPR_RS02360
• Genome accession: NC_003098
• Coordinates: 467597..468646 (+)
• Length: 349 a.a.
• NCBI ID: WP_000653770.1
• Uniprot ID: Q8DQW6
• Organism: Streptococcus pneumoniae R6
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 462597..473646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPR_RS02335	-	463883..464239 (+)	357	WP_000114427.1	hypothetical protein	-
SPR_RS02340 (spr0456)	dnaJ	464641..465759 (+)	1119	WP_001066302.1	molecular chaperone DnaJ	-
SPR_RS02345 (spr0457)	-	466094..466381 (-)	288	WP_000777760.1	hypothetical protein	-
SPR_RS02350 (spr0458)	-	466391..466801 (-)	411	WP_001278301.1	HIT family protein	-
SPR_RS02355 (spr0459)	pptA	466869..467600 (+)	732	WP_000889919.1	ABC transporter ATP-binding protein	Regulator
SPR_RS02360 (spr0460)	pptB	467597..468646 (+)	1050	WP_000653770.1	ABC transporter permease	Regulator
SPR_RS02365 (spr0461)	-	468814..469143 (-)	330	WP_000132569.1	hypothetical protein	-
SPR_RS02370 (spr0462)	-	469419..469757 (+)	339	WP_000682124.1	LytTR family DNA-binding domain-containing protein	-
SPR_RS02375 (spr0463)	comE/blpR	469762..470499 (+)	738	WP_001219139.1	response regulator transcription factor	Regulator
SPR_RS02380 (spr0464)	-	470513..471853 (+)	1341	WP_001017622.1	sensor histidine kinase	-
SPR_RS02385 (spr0465)	blpC	471895..472050 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
SPR_RS02390 (spr0466)	-	472107..473468 (-)	1362	Protein_465	bacteriocin secretion accessory protein	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 40556.62 Da
• Isoelectric Point: 10.0008

>NTDB_id=22278 SPR_RS02360 WP_000653770.1 467597..468646(+) (pptB) [Streptococcus pneumoniae R6]
MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYSQLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEA
PDKLFLLVGEEEIKLHLKRQTGISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNLYLRSYLRNGDLFAISLRLLLLS
VLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFDYQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQE
KLALLALLGAGLVLLVLYLPYQVKRQMQD

Nucleotide

• Length: 1050 bp

>NTDB_id=22278 SPR_RS02360 WP_000653770.1 467597..468646(+) (pptB) [Streptococcus pneumoniae R6]
ATGAAAGACTTGTTTTTAAAGAGAAAGCAGGCCTTTCGTAAGGAGTGTCTTGGTTATCTGCGCTATGTGCTCAATGACCA
CTTTGTCTTGTTCCTGCTTGTCCTGTTGGGCTTTCTAGCCTACCAGTACAGTCAACTCTTACAACATTTTCCTGAAAATC
ATTGGCCTATCCTTTTGTTTGTAGGAATTACGTCTGTTTTACTCTTACTTTGGGGAGGAATTGCCACCTATATGGAGGCT
CCAGACAAGCTCTTTCTCTTAGTTGGAGAAGAGGAAATCAAGCTCCATCTCAAGCGTCAAACTGGCATTTCCCTAGTCTT
TTGGCTCTTTGTACAGACCCTTTTCTTGCTGTTATTTGCGCCTTTATTTTTAGCAATGGGTTATGGCTTGCCAGTTTTTC
TGCTCTATGTGCTTTTATTGGGGGTAGGAAAATATTTCCACTTTCGTCAAAAGGCCAGCAAATTTTTTACTGAAACTGGA
CTGGACTGGGACTATGTTATTTCTCAAGAAAGCAAGCGTAAGCAAGTCTTGCTTCGTTTCTTTGCCCTCTTTACGCAGGT
CAAGGGAATTTCAAACAGCGTTAAGCGTCGTGCCTATCTGGACTTTATCTTAAAGGCTGTTCAGAAGGTGCCTGGGAAGA
TTTGGCAAAATCTCTATCTGCGTTCTTATCTGCGAAATGGCGACCTCTTTGCTATCAGTCTTCGTCTTCTATTACTTTCC
GTACTGGCGCAGGTTTTTATCGAGCAAGCTTGGATTGCGACAGCAGTGGTAGTTCTCTTTAACTACCTCTTGCTCTTCCA
GTTGCTGGCCCTCTATCATGCCTTTGACTACCAGTATTTGACCCAACTCTTTCCGCTGGACAAGGGGCAAAAGGAAAAAG
GCTTACAGGAGGTAGTTCGAGGATTGACCAGTTTTGTTTTACTTGTGGAATTAGTTGTTGGGTTGATTACCTTCCAAGAA
AAACTGGCCCTTCTAGCCTTACTAGGAGCTGGTTTGGTTTTACTAGTCTTGTATTTGCCTTATCAGGTAAAACGTCAGAT
GCAGGACTAA

Domains

Predicted by InterProScan.

• Bacterial ABC transporter protein EcsB (EcsB) (2-156)

• Bacterial ABC transporter protein EcsB (EcsB) (158-331)

3D structure

• AlphaFold DB: Q8DQW6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptB	Streptococcus salivarius strain HSISS4	47.429	100	0.476
pptB	Streptococcus thermophilus LMD-9	46.571	100	0.467