Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J49_RS14140 Genome accession   NZ_CP020421
Coordinates   161037..161501 (+) Length   154 a.a.
NCBI ID   WP_162467384.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_210     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 161202..172086 161037..161501 flank -299


Gene organization within MGE regions


Location: 161037..172086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J49_RS14140 comE 161037..161501 (+) 465 WP_162467384.1 ComEA family DNA-binding protein Machinery gene
  A6J49_RS01105 (A6J49_01045) comP 161589..162038 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  A6J49_RS01110 (A6J49_01050) - 162128..162522 (-) 395 Protein_176 5'-nucleotidase -
  A6J49_RS01115 (A6J49_13035) - 162653..162805 (-) 153 WP_002223150.1 hypothetical protein -
  A6J49_RS01125 (A6J49_01060) - 163159..163803 (+) 645 WP_002223148.1 hypothetical protein -
  A6J49_RS01130 (A6J49_01065) - 163819..164910 (+) 1092 WP_002225876.1 XRE family transcriptional regulator -
  A6J49_RS01135 (A6J49_01070) - 164943..166727 (-) 1785 Protein_180 DUF3418 domain-containing protein -
  A6J49_RS14935 - 167100..168326 (-) 1227 Protein_181 DUF3418 domain-containing protein -
  A6J49_RS01140 (A6J49_01075) lpt3 168428..170005 (-) 1578 WP_002223145.1 lipooligosaccharide phosphoethanolamine transferase -
  A6J49_RS01145 (A6J49_01080) - 170217..170399 (-) 183 WP_002223144.1 hypothetical protein -
  A6J49_RS01150 (A6J49_01085) - 170443..172086 (-) 1644 WP_002223143.1 DUF4435 domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 10.9585

>NTDB_id=222690 A6J49_RS14140 WP_162467384.1 161037..161501(+) (comE) [Neisseria meningitidis strain FDAARGOS_210]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=222690 A6J49_RS14140 WP_162467384.1 161037..161501(+) (comE) [Neisseria meningitidis strain FDAARGOS_210]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGACCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment