Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   A6J49_RS01105 Genome accession   NZ_CP020421
Coordinates   161589..162038 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria meningitidis strain FDAARGOS_210     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 161202..172086 161589..162038 within 0


Gene organization within MGE regions


Location: 161202..172086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J49_RS01105 (A6J49_01045) comP 161589..162038 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  A6J49_RS01110 (A6J49_01050) - 162128..162522 (-) 395 Protein_176 5'-nucleotidase -
  A6J49_RS01115 (A6J49_13035) - 162653..162805 (-) 153 WP_002223150.1 hypothetical protein -
  A6J49_RS01125 (A6J49_01060) - 163159..163803 (+) 645 WP_002223148.1 hypothetical protein -
  A6J49_RS01130 (A6J49_01065) - 163819..164910 (+) 1092 WP_002225876.1 XRE family transcriptional regulator -
  A6J49_RS01135 (A6J49_01070) - 164943..166727 (-) 1785 Protein_180 DUF3418 domain-containing protein -
  A6J49_RS14935 - 167100..168326 (-) 1227 Protein_181 DUF3418 domain-containing protein -
  A6J49_RS01140 (A6J49_01075) lpt3 168428..170005 (-) 1578 WP_002223145.1 lipooligosaccharide phosphoethanolamine transferase -
  A6J49_RS01145 (A6J49_01080) - 170217..170399 (-) 183 WP_002223144.1 hypothetical protein -
  A6J49_RS01150 (A6J49_01085) - 170443..172086 (-) 1644 WP_002223143.1 DUF4435 domain-containing protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=222650 A6J49_RS01105 WP_002214937.1 161589..162038(+) (comP) [Neisseria meningitidis strain FDAARGOS_210]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=222650 A6J49_RS01105 WP_002214937.1 161589..162038(+) (comP) [Neisseria meningitidis strain FDAARGOS_210]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACCAAGTGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment