Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilV   Type   Machinery gene
Locus tag   A6J49_RS08130 Genome accession   NZ_CP020421
Coordinates   1384872..1385480 (-) Length   202 a.a.
NCBI ID   WP_061706010.1    Uniprot ID   -
Organism   Neisseria meningitidis strain FDAARGOS_210     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1369255..1386172 1384872..1385480 within 0


Gene organization within MGE regions


Location: 1369255..1386172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J49_RS08000 (A6J49_07695) - 1369354..1369779 (+) 426 WP_002219430.1 hypothetical protein -
  A6J49_RS08005 (A6J49_07700) - 1370023..1370223 (+) 201 WP_002219431.1 hypothetical protein -
  A6J49_RS08010 (A6J49_07705) - 1370291..1370650 (+) 360 WP_002219432.1 hypothetical protein -
  A6J49_RS08015 (A6J49_07710) - 1370675..1371529 (+) 855 WP_002219433.1 YfdQ family protein -
  A6J49_RS08020 (A6J49_07715) - 1371599..1371814 (+) 216 WP_002219434.1 hypothetical protein -
  A6J49_RS08025 (A6J49_07720) - 1371849..1372109 (+) 261 WP_002223443.1 NGO1622 family putative holin -
  A6J49_RS08030 (A6J49_07725) - 1372106..1372399 (+) 294 WP_002220689.1 hypothetical protein -
  A6J49_RS08035 (A6J49_07730) - 1372402..1372593 (+) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  A6J49_RS08040 (A6J49_07735) - 1372593..1372733 (+) 141 WP_002225349.1 hypothetical protein -
  A6J49_RS08045 (A6J49_07740) - 1372730..1372939 (+) 210 WP_002220687.1 hypothetical protein -
  A6J49_RS08050 (A6J49_07745) - 1372997..1373914 (-) 918 WP_002219437.1 KilA-N domain-containing protein -
  A6J49_RS08055 (A6J49_07750) - 1374783..1375139 (-) 357 WP_002223441.1 DUF4760 domain-containing protein -
  A6J49_RS08065 (A6J49_07760) - 1375687..1376067 (-) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  A6J49_RS08070 (A6J49_07765) - 1376180..1377252 (-) 1073 Protein_1327 tyrosine-type recombinase/integrase -
  A6J49_RS08085 (A6J49_07780) yaaA 1377781..1378560 (-) 780 WP_002225351.1 peroxide stress protein YaaA -
  A6J49_RS15145 - 1378609..1378734 (-) 126 Protein_1329 IS5/IS1182 family transposase -
  A6J49_RS08090 (A6J49_07785) dapC 1378823..1380010 (-) 1188 WP_002225352.1 succinyldiaminopimelate transaminase -
  A6J49_RS08095 (A6J49_07790) dut 1380088..1380540 (-) 453 WP_002225353.1 dUTP diphosphatase -
  A6J49_RS08100 (A6J49_07795) - 1380740..1381108 (+) 369 Protein_1332 AzlC family ABC transporter permease -
  A6J49_RS08115 (A6J49_07805) pilX 1382877..1383350 (-) 474 WP_002225356.1 PilX family type IV pilin Machinery gene
  A6J49_RS08120 (A6J49_07810) pilK 1383355..1383954 (-) 600 WP_105165303.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  A6J49_RS08125 (A6J49_07815) - 1383933..1384875 (-) 943 Protein_1335 PilW family protein -
  A6J49_RS08130 (A6J49_07820) pilV 1384872..1385480 (-) 609 WP_061706010.1 type IV pilus modification protein PilV Machinery gene
  A6J49_RS08135 (A6J49_07825) pilH 1385504..1386172 (-) 669 WP_002230433.1 Tfp pilus assembly protein FimT/FimU Machinery gene

Sequence

Protein


Download         Length: 202 a.a.        Molecular weight: 21876.75 Da        Isoelectric Point: 4.8040

>NTDB_id=222669 A6J49_RS08130 WP_061706010.1 1384872..1385480(-) (pilV) [Neisseria meningitidis strain FDAARGOS_210]
MKNNDCFRLKDSQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYMGNHTLSAVDGDFAIDAMKTKGQLAEAQLKRFSYELKNALPDAAAIHYAVCKDSSGNAPTLSGNAFSSNCDNKANG
DTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE

Nucleotide


Download         Length: 609 bp        

>NTDB_id=222669 A6J49_RS08130 WP_061706010.1 1384872..1385480(-) (pilV) [Neisseria meningitidis strain FDAARGOS_210]
ATGAAGAATAATGATTGCTTCCGCCTGAAAGATTCCCAGTCCGGTATGGCGCTGATAGAAGTCTTGGTTGCTATGCTCGT
TCTGACCATCGGTATTTTGGCACTATTGTCTGTACAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAGGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACATGGGAAACCATACACTATCAGCTGTGGATGGCGATTTTGCGATTGATGCCATGAAAACTAAGGGGCA
ATTGGCAGAGGCACAATTGAAGAGATTTAGTTATGAGCTGAAAAATGCCTTGCCGGATGCGGCAGCCATCCATTACGCCG
TCTGCAAGGATTCGTCGGGTAACGCGCCGACATTGTCCGGCAATGCTTTTTCTTCAAATTGCGACAATAAGGCAAACGGG
GATACTTTAATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGAGGTGAGCGG
CGACAATATCGTATATACTTATCAGGCAAGGGTCGGAGGTCGGGAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-36)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilV Neisseria meningitidis 8013

96.602

100

0.985
  pilI Neisseria gonorrhoeae MS11

84.158

100

0.842
  pilV Neisseria gonorrhoeae MS11

84.158

100

0.842

Multiple sequence alignment