Detailed information
Bioinformatically predicted
Overview
| Name | pilI | Type | Machinery gene |
| Locus tag | A6J46_RS10170 | Genome accession | NZ_CP020419 |
| Coordinates | 1743879..1744496 (-) | Length | 205 a.a. |
| NCBI ID | WP_082298766.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain FDAARGOS_207 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1695234..1756831 | 1743879..1744496 | within | 0 |
Gene organization within MGE regions
Location: 1695234..1756831
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6J46_RS09850 (A6J46_09935) | - | 1695234..1695716 (+) | 483 | Protein_1693 | KilA-N domain-containing protein | - |
| A6J46_RS09855 (A6J46_09940) | - | 1695962..1696879 (+) | 918 | WP_082298751.1 | Bro-N domain-containing protein | - |
| A6J46_RS09860 (A6J46_09945) | - | 1696921..1697472 (-) | 552 | WP_082298752.1 | DUF4760 domain-containing protein | - |
| A6J46_RS14370 (A6J46_13485) | - | 1697751..1697882 (+) | 132 | WP_105211406.1 | hypothetical protein | - |
| A6J46_RS09870 (A6J46_09950) | - | 1697879..1698247 (+) | 369 | WP_082298753.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| A6J46_RS13775 | - | 1698292..1698441 (-) | 150 | WP_047949669.1 | hypothetical protein | - |
| A6J46_RS09875 (A6J46_09960) | - | 1698444..1699118 (-) | 675 | WP_003693436.1 | hypothetical protein | - |
| A6J46_RS09880 (A6J46_09965) | - | 1699115..1699600 (-) | 486 | WP_003693438.1 | hypothetical protein | - |
| A6J46_RS09885 (A6J46_09970) | - | 1699606..1700079 (-) | 474 | WP_082298754.1 | hypothetical protein | - |
| A6J46_RS09890 (A6J46_09975) | - | 1700135..1701430 (-) | 1296 | WP_003693441.1 | DUF4043 family protein | - |
| A6J46_RS09895 (A6J46_09980) | - | 1701451..1702011 (-) | 561 | WP_226876107.1 | hypothetical protein | - |
| A6J46_RS09900 (A6J46_13490) | - | 1702056..1702367 (-) | 312 | WP_125460706.1 | hypothetical protein | - |
| A6J46_RS09905 (A6J46_09985) | - | 1702435..1703628 (-) | 1194 | WP_082298755.1 | hypothetical protein | - |
| A6J46_RS09910 (A6J46_09990) | - | 1703616..1706822 (-) | 3207 | WP_082298756.1 | hypothetical protein | - |
| A6J46_RS09915 (A6J46_09995) | - | 1706825..1707205 (-) | 381 | WP_082298757.1 | hypothetical protein | - |
| A6J46_RS09920 (A6J46_10000) | - | 1707205..1708092 (-) | 888 | WP_082298758.1 | hypothetical protein | - |
| A6J46_RS09925 (A6J46_10005) | - | 1708085..1708510 (-) | 426 | WP_082298759.1 | hypothetical protein | - |
| A6J46_RS09930 (A6J46_10010) | - | 1708522..1708929 (-) | 408 | WP_082298808.1 | hypothetical protein | - |
| A6J46_RS09935 (A6J46_10015) | - | 1709027..1716778 (-) | 7752 | WP_192941164.1 | PLxRFG domain-containing protein | - |
| A6J46_RS09945 (A6J46_10025) | - | 1716775..1717971 (-) | 1197 | WP_082298760.1 | hypothetical protein | - |
| A6J46_RS09950 (A6J46_10030) | - | 1718210..1720477 (-) | 2268 | WP_226876108.1 | hypothetical protein | - |
| A6J46_RS09955 (A6J46_10035) | - | 1720462..1721736 (-) | 1275 | WP_082298762.1 | PBSX family phage terminase large subunit | - |
| A6J46_RS14150 | - | 1721717..1722256 (-) | 540 | WP_226876110.1 | hypothetical protein | - |
| A6J46_RS09970 (A6J46_10050) | - | 1722256..1722678 (-) | 423 | WP_003690919.1 | hypothetical protein | - |
| A6J46_RS09975 (A6J46_10055) | - | 1722743..1723261 (-) | 519 | WP_003693459.1 | HNH endonuclease | - |
| A6J46_RS09980 (A6J46_10060) | - | 1723252..1723635 (-) | 384 | WP_003690918.1 | recombination protein NinB | - |
| A6J46_RS09985 (A6J46_10065) | - | 1723632..1723937 (-) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| A6J46_RS09990 (A6J46_10070) | - | 1723930..1724367 (-) | 438 | WP_226876111.1 | RusA family crossover junction endodeoxyribonuclease | - |
| A6J46_RS14155 | - | 1724358..1724627 (-) | 270 | WP_047921130.1 | hypothetical protein | - |
| A6J46_RS09995 (A6J46_10075) | - | 1724656..1724805 (-) | 150 | WP_003689110.1 | hypothetical protein | - |
| A6J46_RS10000 (A6J46_10080) | - | 1724982..1725476 (-) | 495 | WP_047923539.1 | DUF3310 domain-containing protein | - |
| A6J46_RS10005 (A6J46_10085) | - | 1725551..1725799 (-) | 249 | WP_105211409.1 | hypothetical protein | - |
| A6J46_RS10010 (A6J46_10090) | - | 1725792..1726574 (-) | 783 | WP_025456432.1 | ATP-binding protein | - |
| A6J46_RS10015 (A6J46_10095) | - | 1726590..1727624 (-) | 1035 | WP_082298682.1 | helix-turn-helix domain-containing protein | - |
| A6J46_RS10020 (A6J46_10100) | - | 1727621..1727848 (-) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| A6J46_RS10025 (A6J46_10105) | - | 1728022..1728210 (+) | 189 | WP_003706568.1 | hypothetical protein | - |
| A6J46_RS10030 (A6J46_10110) | - | 1728187..1728342 (-) | 156 | WP_047923772.1 | hypothetical protein | - |
| A6J46_RS10035 (A6J46_10115) | - | 1728422..1728637 (-) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| A6J46_RS10040 (A6J46_10120) | - | 1728765..1729469 (+) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| A6J46_RS10045 (A6J46_10125) | - | 1729629..1730168 (+) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| A6J46_RS10050 (A6J46_10130) | - | 1730169..1730528 (+) | 360 | WP_003691733.1 | hypothetical protein | - |
| A6J46_RS10055 (A6J46_10135) | - | 1730545..1730763 (-) | 219 | WP_003691731.1 | hypothetical protein | - |
| A6J46_RS10060 (A6J46_10140) | - | 1731375..1731707 (+) | 333 | WP_003696914.1 | hypothetical protein | - |
| A6J46_RS10065 (A6J46_10145) | - | 1731860..1732135 (+) | 276 | WP_003695501.1 | NGO1622 family putative holin | - |
| A6J46_RS10070 (A6J46_10150) | - | 1732132..1732293 (+) | 162 | WP_004464809.1 | hypothetical protein | - |
| A6J46_RS10075 (A6J46_10155) | - | 1732362..1733048 (+) | 687 | WP_010359969.1 | phage replication initiation protein, NGO0469 family | - |
| A6J46_RS10080 (A6J46_10160) | - | 1733188..1733370 (+) | 183 | WP_003691535.1 | hypothetical protein | - |
| A6J46_RS10085 (A6J46_10165) | - | 1733367..1733858 (+) | 492 | WP_010359966.1 | siphovirus Gp157 family protein | - |
| A6J46_RS14515 | - | 1734157..1734423 (+) | 267 | Protein_1741 | hypothetical protein | - |
| A6J46_RS10100 (A6J46_10180) | - | 1734704..1735387 (+) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| A6J46_RS10105 (A6J46_10185) | - | 1735582..1735851 (+) | 270 | WP_003687928.1 | hypothetical protein | - |
| A6J46_RS10115 (A6J46_10195) | - | 1736207..1737403 (-) | 1197 | WP_105211410.1 | integrase arm-type DNA-binding domain-containing protein | - |
| A6J46_RS10130 (A6J46_10210) | yaaA | 1737933..1738712 (-) | 780 | WP_047951699.1 | peroxide stress protein YaaA | - |
| A6J46_RS10135 (A6J46_10215) | dapC | 1738868..1740055 (-) | 1188 | WP_082298765.1 | succinyldiaminopimelate transaminase | - |
| A6J46_RS10140 (A6J46_10220) | dut | 1740133..1740585 (-) | 453 | WP_047925987.1 | dUTP diphosphatase | - |
| A6J46_RS10145 (A6J46_13495) | - | 1740751..1741462 (+) | 712 | Protein_1748 | AzlC family ABC transporter permease | - |
| A6J46_RS10150 (A6J46_10230) | - | 1741459..1741767 (+) | 309 | WP_010951048.1 | AzlD family protein | - |
| A6J46_RS10155 (A6J46_10235) | pilL | 1741837..1742310 (-) | 474 | WP_025456309.1 | PilX family type IV pilin | Machinery gene |
| A6J46_RS10160 (A6J46_10240) | pilK | 1742312..1742923 (-) | 612 | WP_010951047.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| A6J46_RS10165 (A6J46_10245) | pilJ | 1742902..1743882 (-) | 981 | WP_105211411.1 | PilW family protein | Machinery gene |
| A6J46_RS10170 (A6J46_10250) | pilI | 1743879..1744496 (-) | 618 | WP_082298766.1 | type IV pilus modification protein PilV | Machinery gene |
| A6J46_RS10175 (A6J46_10255) | - | 1744528..1745190 (-) | 663 | Protein_1754 | GspH/FimT family pseudopilin | - |
| A6J46_RS10185 (A6J46_10260) | dnaB | 1745498..1746904 (-) | 1407 | WP_082298767.1 | replicative DNA helicase | - |
| A6J46_RS10195 (A6J46_10270) | - | 1747068..1747650 (+) | 583 | Protein_1756 | superoxide dismutase | - |
| A6J46_RS10205 (A6J46_10280) | - | 1747880..1748389 (-) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| A6J46_RS10210 (A6J46_10285) | - | 1748719..1749051 (-) | 333 | WP_003687908.1 | hypothetical protein | - |
| A6J46_RS10215 (A6J46_10290) | cysT | 1749232..1750061 (+) | 830 | Protein_1759 | sulfate ABC transporter permease subunit CysT | - |
| A6J46_RS10220 (A6J46_10295) | cysW | 1750250..1751110 (+) | 861 | WP_082298768.1 | sulfate ABC transporter permease subunit CysW | - |
| A6J46_RS10225 (A6J46_10300) | - | 1751107..1752183 (+) | 1077 | WP_082298769.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| A6J46_RS10230 (A6J46_10305) | ilvA | 1752239..1753765 (-) | 1527 | WP_033910484.1 | threonine ammonia-lyase, biosynthetic | - |
| A6J46_RS10235 (A6J46_10310) | - | 1753914..1755083 (+) | 1170 | WP_003690889.1 | D-alanyl-D-alanine carboxypeptidase family protein | - |
| A6J46_RS10240 (A6J46_10315) | - | 1755209..1755781 (-) | 573 | WP_050164308.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| A6J46_RS10245 (A6J46_10320) | - | 1755848..1756831 (-) | 984 | WP_003696879.1 | ribose-phosphate pyrophosphokinase | - |
Sequence
Protein
Download Length: 205 a.a. Molecular weight: 22221.08 Da Isoelectric Point: 4.8132
>NTDB_id=222587 A6J46_RS10170 WP_082298766.1 1743879..1744496(-) (pilI) [Neisseria gonorrhoeae strain FDAARGOS_207]
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTELYTPTPSGGDFKFNNNNLISKKDLAKAQLDRFGYELKQALPDAVAIHHAVCKDSSGDAPTLSDSGDFSSNCDDK
ANGDTLIKVLWVNDSAGDSDISRTNLGVSGGNIVYTYQARVGGRE
MKNNDCLRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYTELYTPTPSGGDFKFNNNNLISKKDLAKAQLDRFGYELKQALPDAVAIHHAVCKDSSGDAPTLSDSGDFSSNCDDK
ANGDTLIKVLWVNDSAGDSDISRTNLGVSGGNIVYTYQARVGGRE
Nucleotide
Download Length: 618 bp
>NTDB_id=222587 A6J46_RS10170 WP_082298766.1 1743879..1744496(-) (pilI) [Neisseria gonorrhoeae strain FDAARGOS_207]
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGAGCTGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGTTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGGTTATGAATTGAAACAAGCCTTGCCGGATGCGGTAGCTATTCATC
ACGCCGTCTGCAAGGATTCGTCGGGTGACGCGCCGACATTGTCCGACAGCGGTGATTTTTCTTCAAATTGCGACGATAAG
GCAAACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGG
GGTGAGCGGCGGCAATATCGTATATACTTATCAGGCAAGGGTCGGAGGTCGTGAATGA
ATGAAGAATAATGATTGCTTGCGCCTGAAAAATCCCCAGTCCGGTATGGCGTTGATAGAAGTCTTGGTCGCTATGCTCGT
TCTGACCATCGGTATTTTGGCATTGCTGTCCGTACAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACACGGAGCTGTACACCCCCACTCCCTCTGGCGGCGATTTCAAGTTTAATAATAATAATTTGATAAGTAA
GAAGGATTTGGCAAAAGCCCAGTTGGACAGGTTCGGTTATGAATTGAAACAAGCCTTGCCGGATGCGGTAGCTATTCATC
ACGCCGTCTGCAAGGATTCGTCGGGTGACGCGCCGACATTGTCCGACAGCGGTGATTTTTCTTCAAATTGCGACGATAAG
GCAAACGGGGATACTTTGATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATTTCCCGTACGAATCTTGG
GGTGAGCGGCGGCAATATCGTATATACTTATCAGGCAAGGGTCGGAGGTCGTGAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilI | Neisseria gonorrhoeae MS11 |
90.244 |
100 |
0.902 |
| pilV | Neisseria gonorrhoeae MS11 |
90.244 |
100 |
0.902 |
| pilV | Neisseria meningitidis 8013 |
82.609 |
100 |
0.834 |