Detailed information NTG0222512

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6J44_RS01105
• Genome accession: NZ_CP020418
• Coordinates: 127183..128043 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FDAARGOS_205
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122183..133043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J44_RS01085 (A6J44_01090)	dapD	122693..123514 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
A6J44_RS01090 (A6J44_01095)	pgi	123724..125367 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
A6J44_RS01100 (A6J44_01105)	pilG	125877..127109 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
A6J44_RS01105 (A6J44_01110)	pilD	127183..128043 (+)	861	WP_003689814.1	A24 family peptidase	Machinery gene
A6J44_RS01110 (A6J44_01115)	coaE	128040..128672 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
A6J44_RS01115 (A6J44_01120)	-	128665..128874 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
A6J44_RS01120 (A6J44_01125)	pilF	128960..130636 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6J44_RS01135 (A6J44_01135)	-	130974..131420 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
A6J44_RS01140 (A6J44_01140)	-	131424..132398 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
A6J44_RS01150 (A6J44_01150)	rplU	132622..132930 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=222512 A6J44_RS01105 WP_003689814.1 127183..128043(+) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_205]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=222512 A6J44_RS01105 WP_003689814.1 127183..128043(+) (pilD) [Neisseria gonorrhoeae strain FDAARGOS_205]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441