Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SP_RS09995 Genome accession   NC_003028
Coordinates   1892864..1893763 (-) Length   299 a.a.
NCBI ID   WP_000904858.1    Uniprot ID   A0A0H2URY1
Organism   Streptococcus pneumoniae TIGR4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1887864..1898763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP_RS09975 (SP_1985) rsmA 1888618..1889490 (-) 873 WP_001216856.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  SP_RS09980 (SP_1986) - 1889621..1889929 (-) 309 WP_000333257.1 hypothetical protein -
  SP_RS09985 (SP_1987) - 1889922..1890563 (-) 642 WP_000565531.1 ABC transporter ATP-binding protein -
  SP_RS09990 (SP_1988) - 1890565..1892595 (-) 2031 WP_000825267.1 bacteriocin-associated integral membrane family protein -
  SP_RS09995 (SP_1989) comR 1892864..1893763 (-) 900 WP_000904858.1 helix-turn-helix transcriptional regulator Regulator
  SP_RS10000 (SP_1990) rnmV 1893835..1894395 (-) 561 WP_000660004.1 ribonuclease M5 -
  SP_RS10005 (SP_1991) - 1894395..1895168 (-) 774 WP_000575607.1 TatD family hydrolase -
  SP_RS10010 (SP_1992) - 1895473..1896444 (-) 972 Protein_1889 DUF1542 domain-containing protein -
  SP_RS10015 (SP_1993) rpmH 1896650..1896784 (-) 135 WP_000831905.1 50S ribosomal protein L34 -
  SP_RS10020 (SP_1994) - 1896929..1898143 (-) 1215 WP_000666479.1 pyridoxal phosphate-dependent aminotransferase -
  SP_RS10025 (SP_1995) - 1898299..1898593 (-) 295 Protein_1892 hypothetical protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35409.11 Da        Isoelectric Point: 4.7119

>NTDB_id=22249 SP_RS09995 WP_000904858.1 1892864..1893763(-) (comR) [Streptococcus pneumoniae TIGR4]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=22249 SP_RS09995 WP_000904858.1 1892864..1893763(-) (comR) [Streptococcus pneumoniae TIGR4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.457

97.324

0.365
  comR Streptococcus suis 05ZYH33

37.457

97.324

0.365
  comR Streptococcus pyogenes MGAS8232

36.242

99.666

0.361

Multiple sequence alignment