Detailed information NTG0222428

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: A6J40_RS05165
• Genome accession: NZ_CP020412
• Coordinates: 1122676..1125408 (+)
• Length: 910 a.a.
• NCBI ID: WP_012979015.1
• Uniprot ID: -
• Organism: Legionella longbeachae strain FDAARGOS_201
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1117676..1130408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J40_RS05145 (A6J40_05115)	gstA	1118074..1118676 (-)	603	WP_003632045.1	glutathione transferase GstA	-
A6J40_RS05150 (A6J40_05120)	-	1118735..1119718 (-)	984	WP_003632046.1	hypothetical protein	-
A6J40_RS05155 (A6J40_05125)	-	1119858..1121132 (-)	1275	WP_003632048.1	serine hydrolase	-
A6J40_RS05160 (A6J40_05130)	gltX	1121129..1122544 (-)	1416	WP_003632050.1	glutamate--tRNA ligase	-
A6J40_RS05165 (A6J40_05135)	letS	1122676..1125408 (+)	2733	WP_012979015.1	two-component system sensor histidine kinase LetS	Regulator
A6J40_RS05170 (A6J40_05140)	-	1125449..1126693 (+)	1245	WP_003632052.1	6-phosphofructokinase	-
A6J40_RS05175 (A6J40_05145)	pilA2	1126986..1127420 (+)	435	WP_003632053.1	pilin	Machinery gene
A6J40_RS05180 (A6J40_05150)	-	1127502..1127825 (+)	324	WP_003632054.1	BolA family transcriptional regulator	-
A6J40_RS05185 (A6J40_05155)	-	1128156..1129556 (+)	1401	WP_003632056.1	APC family permease	-
A6J40_RS05195 (A6J40_05160)	-	1129729..1130265 (-)	537	Protein_1010	IS5 family transposase	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102712.32 Da
• Isoelectric Point: 7.7707

>NTDB_id=222428 A6J40_RS05165 WP_012979015.1 1122676..1125408(+) (letS) [Legionella longbeachae strain FDAARGOS_201]
MKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINPE
VKALAFYSSDGQLLAYRGGKHSLNKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADDI
LGWLSLDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGII
EQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITEL
NVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTNVEQETEKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVERNQVHPFAHFKMLCFDDNPMQLEALCNGL
GYWGIKCIAVSSLNQLAKELKDNKDCQIAFLNINKGYEQQITKLIAEHNYFPYVLISKWLINDYAALGAQGFLYKPISIQ
KLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRSNITSVDNGEIAVSVCNEKKFSL
ILLDLRMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKAGVNFCLQKPIDEKQLLIQILRIADKAKHSAI
DWQLCIQKASGNQSLAEEFLARFVEELLKNREEFIQLMHEKNVKQLGEVAHKLHGACCFSGVPTLQKKVVQVEKLAAHAA
SIEELAMPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2733 bp

>NTDB_id=222428 A6J40_RS05165 WP_012979015.1 1122676..1125408(+) (letS) [Legionella longbeachae strain FDAARGOS_201]
TTGAAAAGCATTGGTATAAAGTATCAACTACGAATTACTACTTTAATTCCTGTTTTTCTCGTCGCCCTACTCCTTGCCAT
TTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTTGGTGAAGCATATATCCGGCAATTACTTC
CGGCTGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGCCTAATCAATGCCTCTACAATCAACCCCGAA
GTTAAAGCACTTGCTTTTTATAGTAGCGACGGTCAACTCCTTGCTTATCGTGGTGGCAAACATTCGCTTAACAAACCATT
TACTGCACCTAAATTCACCGGGGATTACATCAAAAGTAAACAAATTAACCCCTTTACTATTAATTTTATCGCGCCGGTTA
CGATTCCAAAATTCAATTTGTATTCCAATTCTTCTTTTAAAAATATTTTAAGTCCCATGGCATCCCGTGCTGATGACATT
CTTGGGTGGTTGTCTCTTGATATTGATACTCGTTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTTCAT
TACTTTATTTGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCCAAACAAATTTATTTACCTATTTCTCGTTTAC
GACGAAGCATGAAACAAATTTTGCGTAACGAGTTTGAAACAGAAATAAAAACAACAAGCTCTGGTGAATTAGGCATAATT
GAACAGGGATGTTCCCATTTGCAAAAAAAACACCTTGAAACGATACGTGATCTAAACCACCACATTGAGGTAGCCACGGC
TGATTTACAACAAAGTTTGGAACTCTTGGAAGAAAAAAATATTGAACTCTCCCTCGAAAAGAAAAAAATTGAAGAAAAAA
GTCGGCAAAAATCTGAGTTCATAGCCAATATGAGCCATGAAATTCGTACGCCGATGAATGGAGTTATTGGTTTTACTAAC
GTTTTGCTTGAAAGTAAACTCGATCCATTACAACTGGATTATGTAAAAACAATTAAATCATCAGCACAAGACTTATTAGG
GATTATCAATGATATTCTCGATTTCTCAAAAATTGATGCAGGAAAACTTCATCTCGATTGTATTCCGTTAAATATTCGCC
ATTGTATTGATGAAGTACTCGCTCTTGCAGCACCTAATGCCCATAAGAAGGGAATCGACTTAATTCCTATAACAGAACTA
AACGTACCTAAAATTGTTTTAGGGGATCCCTTCAGGGTGAAACAATTCATTAGCAACCTGGTAACTAATGCTGTTAAATT
TACCGATCATGGATATGTATTAATCCGTACCAATGTGGAGCAGGAAACGGAAAAAGATTACACTTTATGCATTACAATTA
CTGATACAGGCCTAGGTATTTCTCCTGAAGACCAAAGCAAATTATTTACAGCCTTCAATCAAGCAGATACAAGTATTACC
CGTCGTTATGGGGGCTCCGGACTTGGCTTGGTAATTTGCAAAAAACTCTGCGAGGAAATGAAAGGCCGTATTACTTTCGC
CAGCGAACTCAACAAAGGTTCTGTATTTACCGCTTATATCAAGGTTGAAAAATTGGTTGCTTATGAAGTTGAAAGAAATC
AAGTGCATCCTTTTGCGCATTTCAAAATGCTTTGTTTTGACGATAACCCAATGCAATTGGAAGCCCTGTGTAATGGCTTA
GGATATTGGGGAATAAAATGTATCGCTGTAAGTTCACTCAATCAACTCGCGAAAGAGCTGAAAGACAATAAAGACTGCCA
AATCGCATTTCTTAATATCAATAAAGGCTACGAACAGCAAATTACCAAGCTAATAGCCGAACATAATTATTTTCCCTATG
TATTAATCTCTAAATGGCTTATCAATGATTATGCAGCACTTGGAGCACAGGGATTTTTATATAAACCCATTAGCATCCAA
AAACTCCAAGATATTATTGAGTCATTAACAAATCAGGAAAATATTGAAAAGTCGGTTAACCATGAATTAGAAGGTTTAAG
GGAACAATTACGTTTCTTACATCCTGATCTTCTTATAGCTGAAGATAATCCAGTAAATAAAATGCTTCTTGATTCTTTAT
TAGGGACTCGTTCCAACATTACATCCGTTGATAATGGCGAAATAGCCGTATCGGTGTGTAATGAAAAGAAATTCAGTCTC
ATCTTGCTTGATTTGCGTATGCCTAAAATAAATGGCTTGGAAGCTGCTCGACTTATCCGCCAAAAATCAGAGTTTAATCG
TCATACACCAATAGTATTGATTAGTGCAAATGGTAGAGATGTTAATGATATTGATTTAAAGAAAGCTGGTGTAAATTTTT
GTTTGCAAAAGCCTATAGACGAAAAACAATTATTAATTCAAATTTTACGTATTGCAGATAAAGCAAAACACTCAGCAATA
GATTGGCAACTATGTATTCAAAAAGCCTCAGGAAATCAATCACTTGCTGAAGAGTTTCTTGCTCGGTTTGTAGAAGAATT
GCTTAAAAATCGTGAAGAGTTTATCCAATTAATGCATGAAAAAAATGTGAAGCAACTGGGCGAAGTGGCGCATAAACTTC
ATGGAGCATGTTGTTTTAGTGGTGTTCCCACGTTACAAAAAAAAGTAGTTCAGGTTGAAAAACTTGCTGCGCATGCTGCT
TCAATCGAAGAGTTAGCTATGCCTTTCGCAGAATTAATTCAAAGCATCGATGCGGTGATTAGTGAATACGAAAATCAAAA
AATAAAAACTTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Single cache domain 4 (sCache_4) (35-179)

• Hpt domain (Hpt) (818-899)

• Response regulator receiver domain (Response_reg) (678-786)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	77.925	99.56	0.776