Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A6J62_RS18345 Genome accession   NZ_CP020408
Coordinates   2726771..2727403 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain FDAARGOS_223     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2721771..2732403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J62_RS18325 (A6J62_18175) - 2721921..2723132 (+) 1212 WP_000215482.1 aspartate aminotransferase family protein -
  A6J62_RS18330 (A6J62_18180) astA 2723272..2724291 (+) 1020 WP_000962042.1 arginine N-succinyltransferase -
  A6J62_RS18335 (A6J62_18185) astD 2724301..2725758 (+) 1458 WP_000150128.1 succinylglutamate-semialdehyde dehydrogenase -
  A6J62_RS18340 (A6J62_18190) - 2725901..2726692 (+) 792 WP_000189091.1 DUF1338 domain-containing protein -
  A6J62_RS18345 (A6J62_18195) crp 2726771..2727403 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  A6J62_RS18350 (A6J62_18200) - 2727646..2728515 (-) 870 WP_001274669.1 phosphoribulokinase -
  A6J62_RS18355 (A6J62_18205) - 2728612..2728821 (-) 210 WP_000586562.1 YheU family protein -
  A6J62_RS18360 (A6J62_18210) - 2728949..2729938 (-) 990 WP_000627574.1 hydrolase -
  A6J62_RS18365 (A6J62_18215) - 2729935..2730420 (-) 486 WP_001278735.1 TIGR02444 family protein -
  A6J62_RS18370 (A6J62_18220) - 2730421..2732337 (-) 1917 WP_000627678.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=222357 A6J62_RS18345 WP_000242749.1 2726771..2727403(-) (crp) [Vibrio cholerae strain FDAARGOS_223]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=222357 A6J62_RS18345 WP_000242749.1 2726771..2727403(-) (crp) [Vibrio cholerae strain FDAARGOS_223]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACACTGATCCACGCGGGTGAGAAAGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTTATCGGTGAGCTTGGCTTGTTTGAAGAAGGC
CAAGAGCGTACAGCTTGGGTTCGTGCTAAAACACCTTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAATTGAT
CCAAGTAAACCCAGATATCTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment