Detailed information NTG0222173

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C2H94_RS04210
• Genome accession: NZ_CP026034
• Coordinates: 748224..749228 (-)
• Length: 334 a.a.
• NCBI ID: WP_003229285.1
• Uniprot ID: P25144
• Organism: Bacillus subtilis strain PK5_52
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 743224..754228

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H94_RS04185 (C2H94_04155)	acuA	744152..744784 (+)	633	WP_014480567.1	acetoin utilization protein acetyltransferase AcuA	-
C2H94_RS04190 (C2H94_04160)	acuB	744811..745455 (+)	645	WP_003229294.1	acetoin utilization AcuB family protein	-
C2H94_RS04195 (C2H94_04165)	acuC	745452..746615 (+)	1164	WP_015714526.1	acetoin utilization protein AcuC	-
C2H94_RS04200 (C2H94_04170)	motS	746628..747353 (-)	726	WP_249849515.1	flagellar motor protein MotS	-
C2H94_RS04205 (C2H94_04175)	motP	747343..748161 (-)	819	WP_014477672.1	flagellar motor protein MotP	-
C2H94_RS04210 (C2H94_04180)	ccpA	748224..749228 (-)	1005	WP_003229285.1	catabolite control protein A	Regulator
C2H94_RS04215 (C2H94_04185)	aroX	749504..750580 (-)	1077	WP_003223454.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
C2H94_RS04220 (C2H94_04190)	ytxJ	750820..751146 (-)	327	WP_249849516.1	bacillithiol system redox-active protein YtxJ	-
C2H94_RS04225 (C2H94_04195)	ytxH	751170..751601 (-)	432	WP_072175304.1	YtxH domain-containing protein	-
C2H94_RS04230 (C2H94_04200)	ytxG	751632..752054 (-)	423	WP_003229276.1	DUF948 domain-containing protein	-
C2H94_RS04235 (C2H94_04205)	murC	752216..753514 (-)	1299	WP_015714530.1	UDP-N-acetylmuramate--L-alanine ligase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36940.34 Da
• Isoelectric Point: 5.0249

>NTDB_id=222173 C2H94_RS04210 WP_003229285.1 748224..749228(-) (ccpA) [Bacillus subtilis strain PK5_52]
MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELA
RGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAI
DYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKK
PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV
ELPHRIELRKSTKS

Nucleotide

• Length: 1005 bp

>NTDB_id=222173 C2H94_RS04210 WP_003229285.1 748224..749228(-) (ccpA) [Bacillus subtilis strain PK5_52]
ATGAGCAATATTACGATCTACGATGTAGCGAGAGAAGCTAATGTAAGCATGGCAACCGTTTCCCGTGTCGTGAACGGCAA
CCCGAATGTAAAACCGACAACGAGGAAAAAAGTCTTGGAAGCCATTGAACGTCTCGGTTACCGTCCAAACGCGGTGGCAA
GAGGGCTGGCAAGTAAAAAAACAACAACTGTAGGTGTCATCATTCCCGATATCTCAAGCATTTTCTATTCAGAGCTTGCA
CGCGGAATTGAAGATATCGCGACAATGTATAAATACAATATTATTTTGAGCAACTCTGACCAAAACATGGAGAAAGAGCT
CCATTTGTTAAACACAATGCTCGGCAAACAAGTGGACGGCATCGTGTTTATGGGCGGAAACATTACGGACGAGCATGTGG
CGGAATTTAAGCGTTCCCCAGTGCCGATCGTACTTGCCGCTTCTGTAGAAGAGCAGGAGGAAACACCGTCAGTCGCTATC
GATTACGAACAGGCGATTTATGATGCTGTGAAGCTTTTGGTTGATAAAGGACATACAGACATCGCATTCGTTTCCGGACC
AATGGCAGAACCGATCAACCGTTCAAAAAAACTCCAAGGCTACAAACGTGCGCTTGAAGAAGCGAACCTTCCGTTTAATG
AACAATTTGTAGCTGAAGGGGATTACACATATGATTCCGGACTCGAAGCACTGCAGCATCTGATGAGCCTGGATAAAAAA
CCGACAGCCATTCTTTCTGCAACTGATGAAATGGCACTCGGCATTATCCATGCCGCTCAGGATCAGGGCTTATCCATTCC
GGAGGATCTCGACATTATCGGTTTTGATAATACAAGATTAAGCCTCATGGTTCGTCCGCAGCTTTCAACAGTTGTTCAGC
CGACATATGATATCGGCGCCGTTGCGATGAGACTGCTGACGAAGCTCATGAATAAAGAGCCGGTTGAAGAGCATATCGTC
GAACTGCCGCACCGTATAGAGCTTAGAAAGTCAACCAAGTCATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (5-50)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-332)

3D structure

• PDB: 1ZVV
• PDB: 2FEP
• PDB: 3OQM
• PDB: 3OQN
• PDB: 3OQO

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	54.545	98.802	0.539
ccpA	Streptococcus gordonii str. Challis substr. CH1	53.636	98.802	0.53
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	50.602	99.401	0.503