Detailed information NTG0222097

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C2H91_RS16225
• Genome accession: NZ_CP026030
• Coordinates: 3256776..3257780 (+)
• Length: 334 a.a.
• NCBI ID: WP_003229285.1
• Uniprot ID: P25144
• Organism: Bacillus subtilis strain PK3_9
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 3251776..3262780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H91_RS16200 (C2H91_16220)	murC	3252470..3253768 (+)	1299	WP_015714530.1	UDP-N-acetylmuramate--L-alanine ligase	-
C2H91_RS16205 (C2H91_16225)	ytxG	3253930..3254352 (+)	423	WP_003229276.1	DUF948 domain-containing protein	-
C2H91_RS16210 (C2H91_16230)	ytxH	3254383..3254838 (+)	456	WP_004398549.1	YtxH domain-containing protein	-
C2H91_RS16215 (C2H91_16235)	ytxJ	3254862..3255188 (+)	327	WP_015714529.1	bacillithiol system redox-active protein YtxJ	-
C2H91_RS16220 (C2H91_16240)	aroX	3255424..3256500 (+)	1077	WP_003223454.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
C2H91_RS16225 (C2H91_16245)	ccpA	3256776..3257780 (+)	1005	WP_003229285.1	catabolite control protein A	Regulator
C2H91_RS16230 (C2H91_16250)	motP	3257843..3258661 (+)	819	WP_014477672.1	flagellar motor protein MotP	-
C2H91_RS16235 (C2H91_16255)	motS	3258651..3259379 (+)	729	WP_003229290.1	flagellar motor protein MotS	-
C2H91_RS16240 (C2H91_16260)	acuC	3259390..3260553 (-)	1164	WP_015714526.1	acetoin utilization protein AcuC	-
C2H91_RS16245 (C2H91_16265)	acuB	3260550..3261194 (-)	645	WP_064670898.1	acetoin utilization AcuB family protein	-
C2H91_RS16250 (C2H91_16270)	acuA	3261221..3261853 (-)	633	WP_014480567.1	acetoin utilization protein acetyltransferase AcuA	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36940.34 Da
• Isoelectric Point: 5.0249

>NTDB_id=222097 C2H91_RS16225 WP_003229285.1 3256776..3257780(+) (ccpA) [Bacillus subtilis strain PK3_9]
MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELA
RGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAI
DYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKK
PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV
ELPHRIELRKSTKS

Nucleotide

• Length: 1005 bp

>NTDB_id=222097 C2H91_RS16225 WP_003229285.1 3256776..3257780(+) (ccpA) [Bacillus subtilis strain PK3_9]
ATGAGCAATATTACGATCTACGATGTAGCGAGAGAAGCTAATGTAAGCATGGCAACCGTTTCCCGTGTCGTGAACGGCAA
CCCGAATGTAAAACCGACAACGAGGAAAAAAGTCTTGGAAGCCATTGAACGTCTCGGTTACCGTCCAAACGCGGTGGCAA
GAGGGCTGGCAAGTAAAAAAACAACAACTGTAGGTGTCATCATTCCCGATATCTCAAGCATTTTCTATTCAGAGCTTGCA
CGCGGAATTGAAGATATCGCGACAATGTATAAATACAATATTATTTTGAGCAACTCTGACCAAAACATGGAGAAAGAGCT
GCACTTGTTAAACACAATGCTCGGCAAACAAGTGGACGGCATCGTGTTTATGGGCGGAAACATTACGGACGAGCATGTGG
CGGAATTTAAGCGTTCCCCAGTGCCGATTGTACTTGCCGCTTCTGTAGAAGAGCAGGAGGAAACACCGTCAGTCGCTATC
GATTACGAACAGGCGATTTATGATGCTGTGAAGCTTTTGGTTGATAAAGGACATACAGACATCGCATTCGTTTCCGGACC
AATGGCAGAACCGATCAACCGTTCAAAAAAACTCCAAGGCTACAAACGTGCGCTTGAAGAAGCGAACCTTCCGTTTAATG
AACAATTTGTAGCTGAAGGGGATTACACATATGATTCCGGACTCGAAGCACTGCAGCATCTGATGAGCCTGGATAAAAAA
CCGACAGCCATTCTTTCTGCAACTGATGAAATGGCACTCGGCATTATCCATGCCGCTCAGGATCAGGGCTTATCCATTCC
GGAGGATCTCGACATTATCGGCTTTGATAATACAAGATTAAGCCTCATGGTTCGTCCGCAGCTTTCAACAGTTGTTCAGC
CGACATATGATATTGGCGCCGTTGCGATGAGACTGCTGACGAAGCTCATGAATAAAGAGCCGGTTGAAGAGCATATCGTC
GAACTGCCGCACCGTATAGAGCTAAGAAAGTCAACCAAGTCATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (5-50)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-332)

3D structure

• PDB: 1ZVV
• PDB: 2FEP
• PDB: 3OQM
• PDB: 3OQN
• PDB: 3OQO

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	54.545	98.802	0.539
ccpA	Streptococcus gordonii str. Challis substr. CH1	53.636	98.802	0.53
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	50.602	99.401	0.503