Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2H83_RS18235 Genome accession   NZ_CP026028
Coordinates   3484143..3484775 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CIT     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3479143..3489775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H83_RS18205 yheS 3479312..3481225 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2H83_RS18210 yheT 3481225..3482247 (+) 1023 WP_000057356.1 hydrolase -
  C2H83_RS18215 yheU 3482241..3482459 (+) 219 WP_000907085.1 YheU family protein -
  C2H83_RS18220 prkB 3482513..3483382 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2H83_RS18225 yhfA 3483437..3483841 (-) 405 WP_001148908.1 OsmC family protein -
  C2H83_RS18235 crp 3484143..3484775 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2H83_RS18240 yhfK 3484826..3486916 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2H83_RS18245 argD 3486983..3488203 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2H83_RS18250 pabA 3488289..3488852 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2H83_RS18255 fic 3488884..3489486 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2H83_RS18260 yhfG 3489476..3489643 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=221958 C2H83_RS18235 WP_000242755.1 3484143..3484775(+) (crp) [Escherichia coli strain CIT]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=221958 C2H83_RS18235 WP_000242755.1 3484143..3484775(+) (crp) [Escherichia coli strain CIT]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467