Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C2H82_RS16365 Genome accession   NZ_CP026027
Coordinates   3153143..3153802 (+) Length   219 a.a.
NCBI ID   WP_001221495.1    Uniprot ID   P52076
Organism   Escherichia coli strain LIM     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3148143..3158802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H82_RS16335 ygiS 3149426..3151033 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  C2H82_RS16345 mqsA 3151166..3151561 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  C2H82_RS16350 mqsR 3151563..3151859 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  C2H82_RS16355 ygiV 3152064..3152546 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  C2H82_RS16360 ygiW 3152599..3152991 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  C2H82_RS16365 ciaR 3153143..3153802 (+) 660 WP_001221495.1 quorum sensing response regulator transcription factor QseB Regulator
  C2H82_RS16370 qseC 3153799..3155148 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  C2H82_RS16375 ygiZ 3155194..3155526 (-) 333 WP_000917684.1 DUF2645 family protein -
  C2H82_RS16385 mdaB 3155845..3156426 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  C2H82_RS16390 ygiN 3156457..3156771 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  C2H82_RS16395 parE 3156819..3158711 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24677.59 Da        Isoelectric Point: 6.9850

>NTDB_id=221870 C2H82_RS16365 WP_001221495.1 3153143..3153802(+) (ciaR) [Escherichia coli strain LIM]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLSRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=221870 C2H82_RS16365 WP_001221495.1 3153143..3153802(+) (ciaR) [Escherichia coli strain LIM]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGTCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P52076

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361