Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C2H81_RS18235 Genome accession   NZ_CP026026
Coordinates   3484142..3484774 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain CAR     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3479142..3489774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H81_RS18205 yheS 3479311..3481224 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  C2H81_RS18210 yheT 3481224..3482246 (+) 1023 WP_000057356.1 hydrolase -
  C2H81_RS18215 yheU 3482240..3482458 (+) 219 WP_000907085.1 YheU family protein -
  C2H81_RS18220 prkB 3482512..3483381 (+) 870 WP_001274680.1 phosphoribulokinase -
  C2H81_RS18225 yhfA 3483436..3483840 (-) 405 WP_001148908.1 OsmC family protein -
  C2H81_RS18235 crp 3484142..3484774 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C2H81_RS18240 yhfK 3484825..3486915 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C2H81_RS18245 argD 3486982..3488202 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C2H81_RS18250 pabA 3488288..3488851 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  C2H81_RS18255 fic 3488883..3489485 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C2H81_RS18260 yhfG 3489475..3489642 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=221795 C2H81_RS18235 WP_000242755.1 3484142..3484774(+) (crp) [Escherichia coli strain CAR]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=221795 C2H81_RS18235 WP_000242755.1 3484142..3484774(+) (crp) [Escherichia coli strain CAR]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment