Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CYK57_RS06065 Genome accession   NZ_CP026009
Coordinates   1335498..1336163 (+) Length   221 a.a.
NCBI ID   WP_005619495.1    Uniprot ID   A0ABM6X4X3
Organism   Actinobacillus pleuropneumoniae strain App6     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1330498..1341163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CYK57_RS06040 (CYK57_01230) fabB 1331106..1332326 (+) 1221 WP_009875222.1 beta-ketoacyl-ACP synthase I -
  CYK57_RS06045 - 1332518..1333848 (+) 1331 Protein_1180 IS3 family transposase -
  CYK57_RS06050 (CYK57_01235) - 1333995..1334342 (+) 348 WP_005612458.1 NirD/YgiW/YdeI family stress tolerance protein -
  CYK57_RS06055 (CYK57_01236) - 1334398..1334994 (+) 597 WP_005608264.1 NirD/YgiW/YdeI family stress tolerance protein -
  CYK57_RS06060 (CYK57_01237) - 1335035..1335409 (+) 375 WP_005615415.1 NirD/YgiW/YdeI family stress tolerance protein -
  CYK57_RS06065 (CYK57_01238) ciaR 1335498..1336163 (+) 666 WP_005619495.1 response regulator Regulator
  CYK57_RS06070 (CYK57_01239) - 1336156..1337532 (+) 1377 WP_005612462.1 ATP-binding protein -
  CYK57_RS06075 (CYK57_01240) - 1337580..1338140 (-) 561 WP_005603079.1 YtfJ family protein -
  CYK57_RS06080 (CYK57_01241) yajC 1338334..1338630 (+) 297 WP_005597904.1 preprotein translocase subunit YajC -
  CYK57_RS06085 (CYK57_01242) secD 1338657..1340504 (+) 1848 WP_011848525.1 protein translocase subunit SecD -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25153.05 Da        Isoelectric Point: 5.7945

>NTDB_id=221572 CYK57_RS06065 WP_005619495.1 1335498..1336163(+) (ciaR) [Actinobacillus pleuropneumoniae strain App6]
MRILLIEDDKLIGDGLKLGLTKQNFVVDWFQDGKLGFEALFSTEYDAVVLDLTLPKMDGLAILKNWRKENLDIPVLILTA
RDTLDERILGFNSGADDYLCKPFALMEVVVRLQALIRRRYKQSSTEITLGDLTIDSSTHKVTLADKEINLTSKEFQLLLL
FASNKDRVLTRSAIEEKLYSWDNDVSSNAMEVYIHNLRKKLGKEWIKTVHGIGYKIGNSDA

Nucleotide


Download         Length: 666 bp        

>NTDB_id=221572 CYK57_RS06065 WP_005619495.1 1335498..1336163(+) (ciaR) [Actinobacillus pleuropneumoniae strain App6]
ATGCGTATTCTACTGATTGAAGACGACAAACTAATCGGTGACGGCTTAAAGCTGGGACTAACCAAACAAAATTTTGTCGT
TGATTGGTTCCAAGACGGTAAATTAGGCTTTGAAGCGTTATTCTCTACCGAATATGATGCGGTCGTTTTGGATTTAACGT
TACCTAAAATGGACGGCTTAGCCATTCTGAAAAATTGGCGTAAAGAAAATCTGGATATTCCGGTTTTAATCTTAACCGCA
AGGGATACGTTAGACGAAAGAATATTGGGATTTAATTCCGGTGCGGACGATTATCTCTGTAAGCCGTTTGCATTAATGGA
AGTGGTCGTCCGTTTACAAGCTCTAATTCGCCGCCGTTATAAACAGAGTTCCACCGAAATTACTCTCGGTGATCTGACGA
TTGACAGCAGTACCCACAAAGTAACCCTTGCCGATAAAGAAATCAATTTAACCTCGAAAGAATTTCAATTGCTGTTACTG
TTTGCCAGTAATAAAGATCGTGTTTTGACGCGTTCCGCTATCGAAGAAAAATTATACAGTTGGGATAACGACGTCAGCAG
TAACGCTATGGAAGTTTATATCCATAATTTACGTAAAAAACTCGGTAAAGAATGGATCAAAACCGTACACGGCATAGGTT
ATAAAATAGGAAATTCAGATGCTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.778

100

0.385
  ciaR Streptococcus pneumoniae D39

37.778

100

0.385
  ciaR Streptococcus pneumoniae R6

37.778

100

0.385
  ciaR Streptococcus pneumoniae TIGR4

37.778

100

0.385
  ciaR Streptococcus mutans UA159

37.9

99.095

0.376