Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   CYK57_RS04020 Genome accession   NZ_CP026009
Coordinates   865563..867584 (-) Length   673 a.a.
NCBI ID   WP_009874701.1    Uniprot ID   A3N031
Organism   Actinobacillus pleuropneumoniae strain App6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 860563..872584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CYK57_RS04000 (CYK57_00800) pepP 861725..863011 (-) 1287 WP_009874699.1 Xaa-Pro aminopeptidase -
  CYK57_RS04005 (CYK57_00801) - 863420..864643 (-) 1224 WP_009874700.1 ATP-binding protein -
  CYK57_RS04010 (CYK57_00802) - 864779..865168 (-) 390 WP_005614926.1 type II toxin-antitoxin system VapC family toxin -
  CYK57_RS04015 (CYK57_00803) - 865169..865429 (-) 261 WP_005604117.1 hypothetical protein -
  CYK57_RS04020 (CYK57_00804) uvrB 865563..867584 (-) 2022 WP_009874701.1 excinuclease ABC subunit UvrB Machinery gene
  CYK57_RS04025 (CYK57_00805) efeO 867761..868573 (+) 813 WP_005607533.1 iron uptake system protein EfeO -
  CYK57_RS04030 (CYK57_00806) efeB 868585..869778 (+) 1194 WP_009874702.1 iron uptake transporter deferrochelatase/peroxidase subunit -
  CYK57_RS04035 (CYK57_00807) - 869789..870409 (+) 621 WP_009874703.1 hypothetical protein -
  CYK57_RS04040 (CYK57_00808) - 870449..871267 (-) 819 WP_005604126.1 PHP domain-containing protein -
  CYK57_RS04045 (CYK57_00809) - 871271..871861 (-) 591 WP_009874704.1 DNA glycosylase -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76678.46 Da        Isoelectric Point: 5.1545

>NTDB_id=221558 CYK57_RS04020 WP_009874701.1 865563..867584(-) (uvrB) [Actinobacillus pleuropneumoniae strain App6]
MSKQGKPFILHSPFKPSGDQPSAIAKLTEGLNDGLAHQTLLGVTGSGKTFTIANVIAQLNRPAMLLAPNKTLAAQLYAEM
KAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINEQIEQMRLSATKSFLERRDTIVVASVSAIYGLGDVDAYMQM
MLHLQLGAIIDQREILARLAELQYTRNDQAFQRSTFRVRGEVIDIFPAESDEIALRVELFDDEIESLSLFDPLTGHSLGK
VPRYTIYPKTHYVTPRERILNAIEEIKQELVERREYFIKENKLLEEQRITQRTQFDIEMMNELGYCSGIENYSRYLSGRK
EGEPPPTLFDYMPADGLLIIDESHVTVPQIGGMYRGDRARKETLVQYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPG
NYELEKSNGDVVDQVVRPTGLLDPIIEVRPVATQVDDVLSEIHKRVAVDERVLITTLTKKMAEDLTDYLDEHGVRVRYLH
SDIDTVERVEIIHDLRMGMFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYGDRI
TNSMQKAITETERRREKQQKYNEEHGITPQALNKKVGELLDIGQTDKPKRGKQAVKVEEKSANTYKPKSRKELEKELKQL
EQQMRDFAKDLEFEKAAAVRDKIGQLKAVLLEV

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=221558 CYK57_RS04020 WP_009874701.1 865563..867584(-) (uvrB) [Actinobacillus pleuropneumoniae strain App6]
ATGAGCAAGCAAGGCAAACCTTTTATTTTACACAGTCCGTTTAAACCGTCTGGTGATCAGCCGTCAGCGATTGCCAAATT
GACCGAAGGGCTAAATGACGGATTGGCGCATCAAACGTTACTGGGGGTAACCGGTTCGGGTAAAACCTTTACCATTGCTA
ATGTGATCGCTCAACTCAATCGTCCGGCAATGTTGCTTGCGCCGAATAAAACGCTTGCCGCTCAGCTGTATGCCGAGATG
AAAGCCTTCTTCCCAGAAAATGCGGTGGAATACTTTGTCTCTTACTATGACTATTACCAACCGGAAGCCTATGTGCCGAG
TAGCGATACTTTTATCGAAAAAGATGCGTCGATTAACGAACAAATCGAACAGATGCGACTGTCGGCAACCAAATCATTCC
TTGAACGCCGAGATACCATTGTAGTTGCTTCTGTTTCAGCCATTTACGGCTTGGGGGACGTGGACGCTTATATGCAAATG
ATGTTGCATTTACAACTGGGGGCGATTATCGATCAACGAGAGATTCTCGCTCGCCTTGCCGAATTGCAATATACTCGCAA
CGATCAAGCATTTCAGCGTTCGACTTTCCGTGTGCGTGGCGAAGTGATTGATATTTTCCCTGCCGAATCGGACGAAATTG
CATTACGTGTTGAATTGTTTGACGATGAAATCGAAAGCCTTTCGTTGTTTGATCCGCTTACCGGACATAGCTTGGGCAAA
GTGCCTCGCTATACCATTTATCCGAAAACGCACTACGTTACCCCTCGTGAACGCATTTTGAATGCGATTGAAGAAATTAA
ACAAGAGTTGGTGGAACGCCGTGAGTATTTCATCAAAGAAAATAAATTATTGGAAGAACAACGCATTACCCAACGCACGC
AATTCGATATTGAAATGATGAATGAGCTGGGCTATTGCTCGGGTATCGAAAACTATTCACGCTACCTGTCGGGCAGAAAA
GAGGGCGAACCGCCTCCGACATTATTCGATTATATGCCGGCGGACGGTTTGCTGATTATTGACGAAAGCCATGTTACCGT
GCCGCAAATCGGCGGTATGTATCGAGGCGACCGAGCCAGAAAAGAAACGCTGGTGCAATACGGTTTCCGTTTGCCTTCAG
CATTGGATAACCGCCCGTTACGCTTTGAAGAATTTGAACGCCTTGCACCACAGACAATTTATGTTTCGGCAACACCGGGC
AATTATGAATTAGAAAAATCAAACGGTGATGTGGTGGATCAAGTGGTTCGCCCAACGGGATTATTAGACCCGATCATAGA
AGTTCGCCCTGTGGCCACGCAAGTTGATGATGTGTTATCGGAAATCCATAAACGAGTGGCGGTTGATGAACGAGTGTTAA
TTACTACGCTAACCAAAAAAATGGCGGAAGATTTAACCGATTATCTCGATGAACACGGCGTGCGTGTGCGTTATTTGCAT
AGCGATATTGATACGGTTGAACGGGTGGAAATTATTCACGACTTGCGAATGGGGATGTTTGACGTATTGGTCGGCATCAA
CTTGTTACGTGAGGGCTTAGATATGCCGGAAGTATCGCTGGTGGCGATTTTAGATGCGGATAAAGAAGGCTTTTTACGTT
CCGAACGTTCATTAATTCAGACCATCGGACGTGCCGCTCGAAACCTCAACGGCAAAGCGATTCTCTACGGCGACCGCATT
ACCAATTCTATGCAAAAAGCGATTACCGAAACCGAACGCCGCCGAGAAAAACAACAAAAATACAACGAAGAACACGGTAT
TACTCCGCAAGCCCTCAACAAAAAAGTAGGCGAATTGCTCGACATCGGACAAACCGACAAGCCGAAACGAGGCAAACAAG
CGGTCAAAGTCGAAGAAAAATCTGCAAATACCTACAAACCAAAATCCCGCAAAGAGCTGGAAAAAGAACTTAAACAGCTC
GAGCAACAAATGCGAGATTTCGCTAAAGATCTCGAGTTTGAAAAAGCGGCAGCGGTAAGGGATAAAATTGGGCAGTTGAA
GGCTGTATTGTTGGAGGTTTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(555-596)

UvrB/uvrC motif (UVR)

(634-668)

UvrB interaction domain (UvrB_inter)

(162-252)

Helicase conserved C-terminal domain (Helicase_C)

(439-547)

Type III restriction enzyme, res subunit (ResIII)

(17-100)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3N031

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

57.53

98.663

0.568
  uvrB Streptococcus pneumoniae R6

57.53

98.663

0.568
  uvrB Streptococcus pneumoniae D39

57.53

98.663

0.568

Multiple sequence alignment