Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXW53_RS13750 Genome accession   NZ_CP025920
Coordinates   2800711..2801343 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 103605     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2795711..2806343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXW53_RS13725 yhfG 2795843..2796010 (+) 168 WP_000736860.1 YhfG family protein -
  CXW53_RS13730 fic 2796000..2796602 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXW53_RS13735 pabA 2796634..2797197 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  CXW53_RS13740 argD 2797283..2798503 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXW53_RS13745 yhfK 2798570..2800660 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CXW53_RS13750 crp 2800711..2801343 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXW53_RS13755 yhfA 2801645..2802049 (+) 405 WP_001148908.1 OsmC family protein -
  CXW53_RS13760 prkB 2802104..2802973 (-) 870 WP_001274680.1 phosphoribulokinase -
  CXW53_RS13765 yheU 2803027..2803245 (-) 219 WP_000907085.1 YheU family protein -
  CXW53_RS13770 yheT 2803239..2804261 (-) 1023 WP_000057405.1 hydrolase -
  CXW53_RS13775 yheS 2804261..2806174 (-) 1914 WP_001404121.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=221242 CXW53_RS13750 WP_000242755.1 2800711..2801343(-) (crp) [Escherichia coli strain 103605]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=221242 CXW53_RS13750 WP_000242755.1 2800711..2801343(-) (crp) [Escherichia coli strain 103605]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467