Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXW77_RS07805 Genome accession   NZ_CP025910
Coordinates   1625896..1626528 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 204446     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1620896..1631528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXW77_RS07780 yhfG 1621028..1621195 (+) 168 WP_000736860.1 YhfG family protein -
  CXW77_RS07785 fic 1621185..1621787 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXW77_RS07790 pabA 1621819..1622382 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  CXW77_RS07795 argD 1622468..1623688 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXW77_RS07800 yhfK 1623755..1625845 (-) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CXW77_RS07805 crp 1625896..1626528 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXW77_RS07810 yhfA 1626830..1627234 (+) 405 WP_001148908.1 OsmC family protein -
  CXW77_RS07815 prkB 1627289..1628158 (-) 870 WP_001274680.1 phosphoribulokinase -
  CXW77_RS07820 yheU 1628212..1628430 (-) 219 WP_000907085.1 YheU family protein -
  CXW77_RS07825 yheT 1628424..1629446 (-) 1023 WP_000057405.1 hydrolase -
  CXW77_RS07830 yheS 1629446..1631359 (-) 1914 WP_001404121.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220981 CXW77_RS07805 WP_000242755.1 1625896..1626528(-) (crp) [Escherichia coli strain 204446]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220981 CXW77_RS07805 WP_000242755.1 1625896..1626528(-) (crp) [Escherichia coli strain 204446]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467