Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CXX05_RS14810 Genome accession   NZ_CP025881
Coordinates   2921596..2922255 (+) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain 503440     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2916596..2927255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX05_RS14790 plsC 2916742..2917479 (-) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -
  CXX05_RS14795 parC 2917713..2919971 (-) 2259 WP_001281894.1 DNA topoisomerase IV subunit A -
  CXX05_RS14800 ygiV 2920517..2920999 (-) 483 WP_000183494.1 GyrI-like domain-containing protein -
  CXX05_RS14805 ygiW 2921052..2921444 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CXX05_RS14810 ciaR 2921596..2922255 (+) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  CXX05_RS14815 qseC 2922252..2923601 (+) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  CXX05_RS14820 ygiZ 2923647..2923979 (-) 333 WP_000912120.1 DUF2645 family protein -
  CXX05_RS14825 mdaB 2924298..2924879 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CXX05_RS14830 ygiN 2924910..2925224 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  CXX05_RS14835 parE 2925272..2927164 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=220751 CXX05_RS14810 WP_001221502.1 2921596..2922255(+) (ciaR) [Escherichia coli strain 503440]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=220751 CXX05_RS14810 WP_001221502.1 2921596..2922255(+) (ciaR) [Escherichia coli strain 503440]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365