Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CXX09_RS16070 Genome accession   NZ_CP025865
Coordinates   3294409..3295068 (-) Length   219 a.a.
NCBI ID   WP_001221502.1    Uniprot ID   B7LGG8
Organism   Escherichia coli strain 504211     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3289409..3300068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX09_RS16045 parE 3289500..3291392 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  CXX09_RS16050 ygiN 3291440..3291754 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  CXX09_RS16055 mdaB 3291785..3292366 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CXX09_RS16060 ygiZ 3292685..3293017 (+) 333 WP_000912120.1 DUF2645 family protein -
  CXX09_RS16065 qseC 3293063..3294412 (-) 1350 WP_000673354.1 quorum sensing histidine kinase QseC -
  CXX09_RS16070 ciaR 3294409..3295068 (-) 660 WP_001221502.1 quorum sensing response regulator transcription factor QseB Regulator
  CXX09_RS16075 ygiW 3295220..3295612 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CXX09_RS16080 ygiV 3295665..3296147 (+) 483 WP_000183494.1 GyrI-like domain-containing protein -
  CXX09_RS16085 parC 3296693..3298951 (+) 2259 WP_001281894.1 DNA topoisomerase IV subunit A -
  CXX09_RS16090 plsC 3299185..3299922 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24745.66 Da        Isoelectric Point: 6.6543

>NTDB_id=220614 CXX09_RS16070 WP_001221502.1 3294409..3295068(-) (ciaR) [Escherichia coli strain 504211]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=220614 CXX09_RS16070 WP_001221502.1 3294409..3295068(-) (ciaR) [Escherichia coli strain 504211]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B7LGG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365