Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX10_RS20470 Genome accession   NZ_CP025862
Coordinates   4099484..4100116 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 504237     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4094484..4105116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX10_RS20445 yheS 4094653..4096566 (+) 1914 WP_001404121.1 ABC transporter ATP-binding protein -
  CXX10_RS20450 yheT 4096566..4097588 (+) 1023 WP_000057405.1 hydrolase -
  CXX10_RS20455 yheU 4097582..4097800 (+) 219 WP_000907085.1 YheU family protein -
  CXX10_RS20460 prkB 4097854..4098723 (+) 870 WP_001274680.1 phosphoribulokinase -
  CXX10_RS20465 yhfA 4098778..4099182 (-) 405 WP_001148908.1 OsmC family protein -
  CXX10_RS20470 crp 4099484..4100116 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX10_RS20475 yhfK 4100167..4102257 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CXX10_RS20480 argD 4102324..4103544 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX10_RS20485 pabA 4103630..4104193 (-) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  CXX10_RS20490 fic 4104225..4104827 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX10_RS20495 yhfG 4104817..4104984 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220534 CXX10_RS20470 WP_000242755.1 4099484..4100116(+) (crp) [Escherichia coli strain 504237]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220534 CXX10_RS20470 WP_000242755.1 4099484..4100116(+) (crp) [Escherichia coli strain 504237]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467