Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CXV92_RS10110 Genome accession   NZ_CP025859
Coordinates   2038842..2039501 (+) Length   219 a.a.
NCBI ID   WP_001221503.1    Uniprot ID   -
Organism   Escherichia coli strain 504239     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2033842..2044501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXV92_RS10085 ygiS 2035125..2036732 (-) 1608 WP_001384150.1 ABC transporter substrate-binding protein -
  CXV92_RS10090 mqsA 2036865..2037260 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  CXV92_RS10095 mqsR 2037262..2037558 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  CXV92_RS10100 ygiV 2037763..2038245 (-) 483 WP_000183494.1 GyrI-like domain-containing protein -
  CXV92_RS10105 ygiW 2038298..2038690 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  CXV92_RS10110 ciaR 2038842..2039501 (+) 660 WP_001221503.1 quorum sensing response regulator transcription factor QseB Regulator
  CXV92_RS10115 qseC 2039498..2040847 (+) 1350 WP_000673355.1 quorum sensing histidine kinase QseC -
  CXV92_RS10120 ygiZ 2040893..2041225 (-) 333 WP_000914690.1 DUF2645 family protein -
  CXV92_RS26765 - 2041232..2041942 (-) 711 WP_000834029.1 hypothetical protein -
  CXV92_RS26770 - 2041945..2042424 (-) 480 WP_000065332.1 Hcp family type VI secretion system effector -
  CXV92_RS10130 mdaB 2042674..2043255 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  CXV92_RS10135 ygiN 2043286..2043600 (+) 315 WP_000958598.1 putative quinol monooxygenase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24711.65 Da        Isoelectric Point: 6.6543

>NTDB_id=220425 CXV92_RS10110 WP_001221503.1 2038842..2039501(+) (ciaR) [Escherichia coli strain 504239]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKELALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=220425 CXV92_RS10110 WP_001221503.1 2038842..2039501(+) (ciaR) [Escherichia coli strain 504239]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGAGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAACTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAATTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.885

100

0.393
  ciaR Streptococcus pneumoniae D39

37.885

100

0.393
  ciaR Streptococcus pneumoniae R6

37.885

100

0.393
  ciaR Streptococcus pneumoniae TIGR4

37.885

100

0.393
  ciaR Streptococcus mutans UA159

35.426

100

0.361