Detailed information NTG0220421

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: B4W66_RS02230
• Genome accession: NZ_CP020027
• Coordinates: 413661..414662 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain STAB090229
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 408661..419662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B4W66_RS02205 (B4W66_02215)	-	409335..410018 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
B4W66_RS02210 (B4W66_02220)	-	410229..411155 (-)	927	WP_076639582.1	glycosyltransferase family 2 protein	-
B4W66_RS02215 (B4W66_02225)	-	411300..411677 (-)	378	WP_076639581.1	VOC family protein	-
B4W66_RS02220 (B4W66_02230)	-	411688..412353 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
B4W66_RS02225 (B4W66_02235)	-	412402..413487 (-)	1086	WP_076639580.1	aminopeptidase P family protein	-
B4W66_RS02230 (B4W66_02240)	ccpA	413661..414662 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
B4W66_RS02235 (B4W66_02245)	-	414793..415791 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
B4W66_RS02240 (B4W66_02250)	-	415793..417127 (+)	1335	WP_076639579.1	glycosyltransferase family 4 protein	-
B4W66_RS02245 (B4W66_02255)	thrS	417549..419492 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=220421 B4W66_RS02230 WP_002985680.1 413661..414662(+) (ccpA) [Streptococcus pyogenes strain STAB090229]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=220421 B4W66_RS02230 WP_002985680.1 413661..414662(+) (ccpA) [Streptococcus pyogenes strain STAB090229]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559